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EC number: 201-302-7
CAS number: 80-70-6
After evaporation or exposure to the air,
the substance will be rapidly degraded by photochemical processes.
Article 13 of Regulation (EC) No 1907/2006, it is laid down that
information on intrinsic properties of substances may be generated by
means other than tests, provided that the conditions set out in Annex
XI (of the same Regulation) are met.
to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used
if (1) the scientific validity of the (Q)SAR model has been
established, (2) the substance falls within the applicability domain
of the (Q)SAR model, (3) the results are adequate for the purpose of
classification and labeling and/or risk assessment and (4) adequate
and reliable documentation of the applied method is provided.
the assessment of 1,1,3,3-Tetramethylguanidine (CAS 80-70-6) (Q)SAR
results were used forphototransformationin
air. The criteria listed in Annex XI of Regulation (EC) No 1907/2006
are considered to be adequately fulfilled and therefore the
endpoint(s) sufficiently covered and suitable for risk assessment.
further experimental studies on phototransformationin
air are not provided.
Based on an estimated OH radical
rate constant of 137.059E-12 cm³/(molecule*sec), the half-life of
1,1,3,3-Tetramethylguanidine (CAS 80-70-6) was calculated to be 2.8 h
(test conditions: sensitizer for indirect photolysis: OH; 0.5 E06
OH/cm³, 24-h day) (BASF SE, 2018). The substances were within the
applicability domain of the model; however, as the substance is a
tertiary amine, the estimate may be highly uncertain (AOPWIN v1.92,
EPI Suite v4.11, BASF SE, 2018). Therefore, after evaporation or
exposure to the air, the product will be rapidly degraded by
after evaporation or exposure to the air 1,1,3,3-Tetramethylguanidine
(CAS 80-70-6) will be rapidly degraded by photochemical processes.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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