Registration Dossier

Diss Factsheets

Environmental fate & pathways

Phototransformation in air

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

After evaporation or exposure to the air, the substance will be rapidly degraded by photochemical processes.

Key value for chemical safety assessment

Half-life in air:
2.8 h
Degradation rate constant with OH radicals:
0 cm³ molecule-1 s-1

Additional information

QSAR-disclaimer

 In Article 13 of Regulation (EC) No 1907/2006, it is laid down that information on intrinsic properties of substances may be generated by means other than tests, provided that the conditions set out in Annex XI (of the same Regulation) are met.

According to Annex XI of Regulation (EC) No 1907/2006 (Q)SAR results can be used if (1) the scientific validity of the (Q)SAR model has been established, (2) the substance falls within the applicability domain of the (Q)SAR model, (3) the results are adequate for the purpose of classification and labeling and/or risk assessment and (4) adequate and reliable documentation of the applied method is provided.

 

For the assessment of 1,1,3,3-Tetramethylguanidine (CAS 80-70-6) (Q)SAR results were used forphototransformationin air. The criteria listed in Annex XI of Regulation (EC) No 1907/2006 are considered to be adequately fulfilled and therefore the endpoint(s) sufficiently covered and suitable for risk assessment.

Therefore, further experimental studies on phototransformationin air are not provided.

Assessment

Based on an estimated OH radical rate constant of 137.059E-12 cm³/(molecule*sec), the half-life of 1,1,3,3-Tetramethylguanidine (CAS 80-70-6) was calculated to be 2.8 h (test conditions: sensitizer for indirect photolysis: OH; 0.5 E06 OH/cm³, 24-h day) (BASF SE, 2018). The substances were within the applicability domain of the model; however, as the substance is a tertiary amine, the estimate may be highly uncertain (AOPWIN v1.92, EPI Suite v4.11, BASF SE, 2018). Therefore, after evaporation or exposure to the air, the product will be rapidly degraded by photochemical processes.

Therefore, after evaporation or exposure to the air 1,1,3,3-Tetramethylguanidine (CAS 80-70-6) will be rapidly degraded by photochemical processes.