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EC number: 942-925-0
CAS number: -
Acute dermal toxicity was examined in male and female Sprague-Dawley
rats in accordance with OECD TG 402 under GLP conditions.The test
substance (2000 mg/kg bw) was applied uniformly over an area which was
approximately 10% of the total body surface area. Test substance were
held in contact with the skin with a porous gauze dresssing and
non-irritating tape throughout the 24-hour exposure period. The
wrappings were removed at 24 hours after applicatiopn. the applied areas
were washed out gently with distilled water. the animals were observed
for clinical signs and mortality and changes of body weight over a
period of 14 days.
No mortality was observed in the present study. Clinical signs related
with the substance were not observed in any animal during the
observaion period. All tested animals showed normal gains in body
weight. In all animals there were no necropsy findings caused by
administration of test substance.
Based on these results the LD50 value was considered to be higher than
2000 mg/kg bw
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