Registration Dossier
Registration Dossier
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EC number: 942-925-0 | CAS number: -
Toxicological Summary
Administrative data
Workers - Hazard via inhalation route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Workers - Hazard via dermal route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
Workers - Hazard for the eyes
Local effects
- Hazard assessment conclusion:
- no hazard identified
Additional information - workers
Azo zinc complex pigment – melamine compound is an unreactive, odorless, brown solid (powder) with a molecular mass of 615.79 g/mol. Using the modified Grain method, the vapor pressure is estimated to be 2.83E-14 Pa at 25 °C. No melting point and no boiling point could be detected up to 300°C. Endothermic reactions were detected indicated by evaporation and/ or decomposition with evolution of gas. According to OECD guideline 110, method B, the particle size distribution of zinc, 5,5'-azobis-2,4,6(1H,3H,5H)-pyrimidinetrione complexes and melamine was determined by scanning electron microscopy method for the sieved fraction (< 100 µm, 14.22 % of total sample) and presented on the basis of calculated mass fractions. The median diameter was 5.33 µm with two main fractions of 6.87 and 92.66 % distributing in the range of 4 -100 µm. In addition, the compound is nearly insoluble (solubility in water: 0.052 mg/l) and the log Pow is estimated to be -3.15.
No compound related adverse effects are reported in a guideline compliant sub-acute toxicity study up to the limit dose of 1000 mg/kg bw/day and, consequently, a DNEL is not required.
Since the compound is a solid, exposure above the general occupational dust value of 10 mg/m³ should be regarded.
General Population - Hazard via inhalation route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
General Population - Hazard via dermal route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
Local effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
General Population - Hazard via oral route
Systemic effects
Long term exposure
- Hazard assessment conclusion:
- no hazard identified
Acute/short term exposure
- Hazard assessment conclusion:
- no hazard identified
DNEL related information
General Population - Hazard for the eyes
Local effects
- Hazard assessment conclusion:
- no hazard identified
Additional information - General Population
Azo zinc complex pigment – melamine compound is an unreactive, odorless, brown solid (powder) with a molecular mass of 615.79 g/mol. Using the modified Grain method, the vapor pressure is estimated to be 2.83E-14 Pa at 25 °C. No melting point and no boiling point could be detected up to 300°C. Endothermic reactions were detected indicated by evaporation and/ or decomposition with evolution of gas. According to OECD guideline 110, method B, the particle size distribution of zinc, 5,5'-azobis-2,4,6(1H,3H,5H)-pyrimidinetrione complexes and melamine was determined by scanning electron microscopy method for the sieved fraction (< 100 µm, 14.22 % of total sample) and presented on the basis of calculated mass fractions. The median diameter was 5.33 µm with two main fractions of 6.87 and 92.66 % distributing in the range of 4 -100 µm. In addition, the compound is nearly insoluble (solubility in water: 0.052 mg/l) and the log Pow is estimated to be -3.15.
No compound related adverse effects are reported in a guideline compliant sub-acute toxicity study up to the limit dose of 1000 mg/kg bw/day and, consequently, a DNEL is not required.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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