Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-580-7 | CAS number: 64-19-7
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
- Migrated from Short description of key information:
Acetic acid is present at physiological pH as acetate and is a key biochemical intermediate in all living organisms. There is a very rare case report of an individual with allergy to weak organic acids, including acetic acid (Tuft & Ettelson, 1956) which is not viewed of wider relevance.
Citation: Tuft MD & Ettelson LN (1956). Canker sores from allergy to weak organic acids (citric and acetic). J Allergy, vol 27 pp 536-543.
Respiratory sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
- Migrated from Short description of key information:
There are no reports of respiratory sensitisation from the available literature, nor would any be expected for this fundamental biochemical intermediate.
Justification for classification or non-classification
There is no data available to indicate sensitising potential for this ubiquitous natural product. Classification under DSD or CPL is not warranted.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
