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Toxicological information

Acute Toxicity: other routes

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Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: No GLP, method sufficiently described, number of animals: 6.

Data source

Reference
Reference Type:
publication
Title:
Monomeric methyl methacrylate studies on toxicity
Author:
Spealman C.R., Main R.J., Haag H.B., Larson P.S.
Year:
1945
Bibliographic source:
Ind. Med. 14: 292-298

Materials and methods

Principles of method if other than guideline:
literature data
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
Methyl methacrylate
EC Number:
201-297-1
EC Name:
Methyl methacrylate
Cas Number:
80-62-6
Molecular formula:
C5H8O2
IUPAC Name:
methyl methacrylate
Test material form:
liquid

Test animals

Species:
guinea pig

Administration / exposure

Route of administration:
intraperitoneal
No. of animals per sex per dose:
6 animals

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
ca. 1 888 mg/kg bw

Applicant's summary and conclusion