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EC number: 201-297-1
CAS number: 80-62-6
Oral LD50 rat: ca. 7900 mg/kg bw (Deichmann 1941)InhalationLC50 rat, 4 h exposition: 29.8 mg/L (Tansy et al. 1980)DermalLD50 rat, 24 h, occlusive conditions: >5000 mg/kg bw (Rohm & Haas 1982)
In an oral toxicity study (Deichmann 1941) in Sprague Dawley rats methyl
methacrylate 4 dose groups with each 10 animals where exposed to doses
from 8.42 to 11.23 g/kg bw.
LD50 was 7900 mg/kg.
Acute inhalation toxicity of methyl methacrylate was tested in Sprague
Dawley rats with 4 hours whole body exposure. 5 dose groups of 10
animals each (5males, 5 females) were tested in cocentrations of 19.5
mg/l (4750 ppm) to 55.3 mg/l (13476 ppm).
LC50 acute: 29.8 mg/l ( 7093 ppm). (Result based on those dose groups
where result was greater than zero and less than 100 % mortality.)
In a dermal acute toxicity study with male New Zealand White rabbits
animlas were tested in three dose groups (2 animals each) and treated
with 0.2; 2.0 and 5.0 g/kg methyl methacrylate occlusive for 24 hours.
No animals died in the tests.
LD50 acute dermal: > 5000 mg/kg
are studies for toxicity using other routes of exposure (i.p.,) using
different species which are not considered being relevant for the
on the results of the available studies, methyl methacrylate is not
required to be classified for its acute toxicity potential according to
Regulation (EC) 1272/2008 requirements.
MMA falls into category 5 for acute
inhalation toxicity - with no classification for the dermal and oral
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