Registration Dossier

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2009
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: reliable, well-documented GLP study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report date:
2009

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
capillary method
Remarks:
additionally: DSC method

Test material

Constituent 1
Chemical structure
Reference substance name:
(2S)-5-amino-2-[(aminoacetyl)amino]-5-oxopentanoic acid
EC Number:
700-144-0
Cas Number:
13115-71-4
Molecular formula:
C7H13N3O4
IUPAC Name:
(2S)-5-amino-2-[(aminoacetyl)amino]-5-oxopentanoic acid
Details on test material:
Physical state: White cristalline powder

Results and discussion

Melting / freezing point
Melting / freezing pt.:
218 °C
Atm. press.:
ca. 1 atm
Decomposition:
yes
Decomp. temp.:
>= 218

Any other information on results incl. tables

Substance changes the color near the melting point, which indicates beginning decomposition. An endothermic process in the range of 130 -165 degrees is assumed to be caused by the release of crystal water.

Applicant's summary and conclusion

Conclusions:
The melting process beginning at 218 °C is superposed by decomposition.