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EC number: 256-032-2
CAS number: 42978-66-5
The study was performed to assess the acute toxicity following oral
administration in Wistar rats in a GLP-compliant study performed
according OECD 423 guideline.
Single doses of 2,000 mg/kg body weight of test material preparations in
doubly distilled water were given to two administration groups of three
fasted female animals, each, by gavage in a sequential manner. After an
observation period of 14 days no mortality occurred. Moreover, no
clinical signs were observed. The mean body weights of the
administration groups increased throughout the study period. No
macroscopic pathologic abnormalities were noted in the animals of the
2,000 mg/kg administration group examined at the end of the observation
Under the conditions of this study, the median lethal dose of the test
item after oral administration was found to be greater than 2,000 mg/kg
body weight in rats.
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