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EC number: 256-032-2
CAS number: 42978-66-5
No data on the long term toxicity of TPGDA on fish are available.
In Annex IX, Section 9.1.6, Column 2
of Regulation (EC) No 1907/2006, it is laid down that long-term toxicity
testing on fish shall be proposed by the registrant if the chemical
safety assessment indicates the need to investigate further the effects
on fish. In Annex XI, Section 3, it is laid down that testing in
accordance with sections 8.6 and 8.7 of Annex VIII and in accordance
with Annex IX may be omitted, based on the exposure scenario(s)
developed in the Chemical Safety Report (“Substance-Tailored
Exposure-Driven Testing”). In accordance with Annex XI Section 3, it can
be demonstrated in the risk assessment that the manufacture and the use
of the substance do not pose an unacceptable risk for all environmental
compartments as the risk characterization ratios (RCRs) of the chemical
safety assessment are below 1 for all compartments (see Chemical Safety
Report Ch. 10). In
addition, the substance is not classifies as a PBT or vPvB substance
(see IUCLID Ch. 2.3). Therefore, and for reasons of animal
welfare, a long-term toxicity test on fish is not provided.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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