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EC number: 256-032-2
CAS number: 42978-66-5
TPGDA is acutely toxic to fish.
For the assessment of the acute
toxicity of TPGDA (CAS 42978-66-5) experimental data are available. A
non-GLP study was conducted with the test item in accordance with DIN 38
412. In this static study Leuciscus idus was used as a test organism.
The substance was dissolved in acetone (1.0 g/100 mL) prior to testing.The
96-h LC50 was determined to be in the range between 4.6 mg/L and 10
mg/L. The 96-h LC50 of 4.6 mg/L was used as a worst-case key value for
the farther derivation of the aquatic PNECs. No analytical monitoring
was performed during the test procedure. However, the test
concentrations are assumed to be stable over the exposure period based
on a sufficient water solubility, a low Henry's Law constant (see IUCLID
Ch. 5.4.2) and a low adsorption potential (log Kow = 2.7, measured, see
IUCLID Ch.4.7; Log Koc = 3, worst-case, estimated, see IUCLID Ch. 5.4.1).
In conclusion, based on the available
experimental data it can be concluded that TPGDA (CAS 42978 -66 -5)
is with high probability acutely toxic for fish.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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