Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Currently viewing:

Administrative data

Endpoint:
biodegradation in water: screening tests
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Use of validated model
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
publication
Title:
Multimedia environmental models: the fugacity approach
Author:
Mackay, D.
Year:
2001
Bibliographic source:
Multimedia environmental models: the fugacity approach. 2nd ed. Lewis, Boca Raton, FL, USA

Materials and methods

Principles of method if other than guideline:
Biowin1:(linear Model Prediction, Biowin2 (Nonlinear model prediction), Biowin3 (Ultimate Biodegredation Timeframe), Biowin 4 (Promary Biodegredation Timeframe), Biowin5 (MITI Linear Model Prediction) and Biowin6 (MITI Non-linear Model Prediction).
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
1,1,1-trifluoroethane
EC Number:
206-996-5
EC Name:
1,1,1-trifluoroethane
Cas Number:
420-46-2
Molecular formula:
C2H3F3
IUPAC Name:
1,1,1-trifluoroethane

Study design

Oxygen conditions:
other: modeled

Results and discussion

% Degradation
Parameter:
probability of ready biodegradability (QSAR/QSPR)
Remarks on result:
not readily biodegradable based on QSAR/QSPR prediction
Details on results:
Biowin1: Does not biodegrade fast; Biowin2: Does not biodegrade fast; Biowin3: Weeks-months; Biowin4: Days-weeks; Biowin5: Biodegrades fast; Biowin6 Does not biodegrade fast.

Any other information on results incl. tables

Biowin1: Does not biodegrade fast; Biowin2: Does not biodegrade fast; Biowin3: Weeks-months; Biowin4: Days-weeks; Biowin5: Biodegrades fast; Biowin6 Does not biodegrade fast.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Remarks:
valid model
Interpretation of results:
not inherently biodegradable
Conclusions:
The conclusion from the models is that HFC-143a will not undergo ready biodegradation
Executive summary:

Biowin1: Does not biodegrade fast; Biowin2: Does not biodegrade fast; Biowin3: Weeks-months; Biowin4: Days-weeks; Biowin5: Biodegrades fast; Biowin6 Does not biodegrade fast. The conclusion from the models is that HFC-143a will not undergo ready biodegradation