Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Additional information

DINP is not mutagenic in vitro in bacterial mutation assays or mammalian gene mutation assay (with and without metabolic activation) and was not clastogenic in a cytogenetic assay in vitro in CHO cells or in an in vivo assay in bone marrow of Fisher 344 rats (BASF, 1986; 1995a; McKee et al., 2000). As reported in the European Union Risk Assessment Report for DINP, negative results were obtained in an in vivo study. This data suggests that DINP is not genotoxic in vivo or in vitro.


Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

No classification for genetic toxicity is indicated according to the general classification and labeling requirements for dangerous substances and preparations (Directive 67-548-EEC) or the classification, labeling, and packaging (CLP) regulation (EC) No 1272/2008.