Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

DINP does not produce acute or chronic toxicity to earthworms or plants at high concentrations of DINP in soil. Since DINP does not pose an acute or chronic hazard to the terrestrial compartment, it is not possible to derive NOECs or PNECs needed for quantitative risk assessment. However, it is possible to qualitatively conclude based on available effects test data that DINP is not harmful to terrestrial organisms. 

Additioanlly phthalate diesters have been shown to be readily metabolized by vertebrates. Studies in rats have shown that the diester is hydrolyzed to a monoester and alcohol, which can both be absorbed in the gastro-intestinal tract more rapidly than the diester(Rowland et al. 1974; Rowland et al. 1977; White et al. 1980). Continued metabolism of the monoester occurs after absorption to form metabolites that can be readily excreted in urine(Albro and Moore 1974). Mackintosh et al (2004) also demonstrated bio-dilution with increased trophic levels. Taken together with a lack of toxicity data suggests a low risk to terrestrial species and/or secondary poisoning.