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EC number: 249-079-5
CAS number: 28553-12-0
does not produce acute or chronic toxicity to earthworms or plants at
high concentrations of DINP in soil. Since DINP does not pose an acute
or chronic hazard to the terrestrial compartment, it is not possible to
derive NOECs or PNECs needed for quantitative risk assessment. However,
it is possible to qualitatively conclude based on available effects test
data that DINP is not harmful to terrestrial organisms.
phthalate diesters have been shown to be readily metabolized by
in rats have shown that the diester is hydrolyzed to a monoester and
alcohol, which can both be absorbed in the gastro-intestinal tract more
rapidly than the diester(Rowland et al. 1974; Rowland et al. 1977; White
et al. 1980). Continued metabolism of the monoester occurs after
absorption to form metabolites that can be readily excreted in
urine(Albro and Moore 1974). Mackintosh et al (2004) also demonstrated
bio-dilution with increased trophic levels. Taken together with a lack
of toxicity data suggests a low risk to terrestrial species and/or
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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