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EC number: 249-079-5
CAS number: 28553-12-0
DINP has a low potential to bioaccumulate in
the environment based on results from a biomagnification food-web field
study, a bioaccumulation dietary lab study with a fish, and a measured
biota-soil accumulation factor (BSAF) for a soil-dwelling invertebrate.
An aquatic food-web study that included 18 marine species, showed that
DINP did not biomagnify, but rather decreased in tissue concentration in
organisms of increasing trophic position. Decreasing concentrations,
also referred to as biodilution, can be quantified by food-web
magnification factors (FWMFs). The FWMF for DINP was 0.46. A FWMF that
is greater than 1.0 is an indication of chemical biomagnification within
a food-web, whereas a value of less than 1.0 indicates biodilution or
dilution from lower to higher trophic levels. The FWMF is consistent
with a laboratory fish bioaccumulation study in which rainbow trout were
fed a DINP spiked diet for 14 days. Results demonstrated limited
bioaccumulation with a lipid normalized biomagnification factor (BMF,
concentration ratio in tissue to that in diet) of 0.1 and rapid
subsequent depuration with a tissue elimination half-life of 1 day. The
half-life of 1 day was used to calculate a BCF in fish of <3
L/kg for DINP. Data
to assess the potential for terrestrial bioaccumulation of DINP were reported
in a 14-day earthworm toxicity study. The BSAF as measured in a natural
soil was 0.018. A BSAF value of <1 indicates a lack of bioaccumulation.
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