Registration Dossier
Registration Dossier
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EC number: 271-974-4 | CAS number: 68647-86-9
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
At present, it is not expected that coconut shell charcoal becomes systemically available at significant amounts. The Particle Size Distribution has been determined using a standard sieve analysis. The particles were found to be large in size, with a mean particle diameter (D(50)) equalling 5.25 mm and an effective size (D10) of 3.52 mm.
For the Read-Across substance charcoal smaller particles could be found: In the granulometry studies performed with three representative charcoal samples only a minor fraction was inhalable (particle sizes ≤ 100 µm) and more importantly only a negligible fraction was respirable (particle sizes ≤ 2 µm). In addition, there is no evidence for a significant translocation of even smaller carbonaceous particles (35 nm) to the systemic circulation upon inhalation (Wiebert et al. 2006).
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