Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 201-279-3 | CAS number: 80-43-3
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Secondary citation in handbook, original reference not available
Data source
Referenceopen allclose all
- Reference Type:
- review article or handbook
- Title:
- Patty's industrial hygiene and toxicology: 2.5.4 Dicumyl peroxide
- Author:
- Clayton GD, Clayton FE
- Year:
- 1 993
- Bibliographic source:
- 572-573, Wiley-Interscience, John Wiley & Sons, New York, NY
- Reference Type:
- secondary source
- Title:
- Bulletin T-104, Revision I
- Author:
- Hercules Rubber Chemicals, Hercules Powder Company
- Year:
- 1 964
- Bibliographic source:
- internal report, not available
Materials and methods
- Type of sensitisation studied:
- skin
- Study type:
- study with volunteers
- Principles of method if other than guideline:
- Patch test
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Bis(α,α-dimethylbenzyl) peroxide
- EC Number:
- 201-279-3
- EC Name:
- Bis(α,α-dimethylbenzyl) peroxide
- Cas Number:
- 80-43-3
- Molecular formula:
- C18H22O2
- IUPAC Name:
- 1,1'-(dioxydipropane-2,2-diyl)dibenzene
Constituent 1
Method
- Type of population:
- not specified
- Controls:
- No data
- Route of administration:
- dermal
Results and discussion
- Results of examinations:
- Slight skin irritation, but no skin sensitisation were reported in 200 human volunteers patch tested with technical grade of 90 % dicumyl peroxide.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
