Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 218-679-9 | CAS number: 2215-35-2
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
In a key delayed contact hypersensitivity study, a group of albino guinea pigs was induced with 5% w/v test substance in mineral oil and then challenged with the same concentration (Costello, BA and Gilman, MR, 1982). All scores at the 24 hour and 48 hour challenge phase readings were zero. The test substance was not a sensitizer in the guinea pig.
In a supporting delayed contact hypersensitivity study, a group of 20 Dunkin-Hartley strain Guinea pigs was induced with 5% w/v test substance in mineral oil and then challenged with the same concentration (Costello, BA and Gilman, MR, 1982). All scores at the 24 hour and 48 hour challenge phase readings were zero. The test substance was not a sensitizer in the guinea pig.
Migrated from Short description of key information:
The substance is not skin-sensitizing to guinea gigs
Respiratory sensitisation
Endpoint conclusion
- Additional information:
no data available
Migrated from Short description of key information:
no data available
Justification for classification or non-classification
In accordance with EU CLP (Regulation (EC) No. 1272/2008), this substance does not meet the criteria for classification as a skin sensitizer.
No data are available for respiratory sensitization.
The substance is therefore not classifiable for this endpoint in accordance to the CLP Regulation (EC) No 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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