Registration Dossier

Administrative data

Description of key information

The substance is  corrosive to eyes and skin in rabbit.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (corrosive)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

The substance is officially classified as R34, R42/43 in accordance with Directive 67/548/EEC, so there is no need to perform tests on irritation/corrosion according to column 2 in REACH Annex VII.


Effects on skin irritation/corrosion: corrosive

Effects on eye irritation: corrosive

Effects on respiratory irritation: highly irritating

Justification for classification or non-classification

Maleic anhydride is officially classified as R34, R42/43 in accordance with Directive 67/548/EEC.