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EC number: 608-544-6
CAS number: 3082-64-2
Acute Oral toxicityRat: LD50 200-500 mg/kg bw (OECD 423); [BASF, 1998; Calvert Preclinical Services, 2000] Acute Inhalation toxicityActually, there is no information available to cover this endpoint.Acute Dermal toxicityActually, there is no information available to cover this endpoint.
Acute Oral toxicity
Currently, there are
no studies available. Nevertheless, there are two reliable studies
existing, which may serve as read across: rac-1 -Phenyl-propylamine (CAS
2941-20-0) and (S)-1 -Phenyl-propylamine (CAS 3789-59-1).
study was accomplished according to OECD 423. The acute oral toxicity of
rac-1-Phenyl-propylamine (read across, CAS 2941-20-0) was determined to
be 200-500 mg/kg bw. Thus, in accordance to the GHS (Globally Harmonised
System), the substance (R)-1-Phenylpropylamine should be classified in
the hazard category 3. [BASF, 1998]
The second study
investigated the acute oral toxicity of (S)-1-Phenylpropylamine (read
across, CAS 3789-59-1) in rats, given doses of 200 mg/kg bw and 2000
mg/kg bw by gavage. In
accordance to the GHS (Globally Harmonised System), the substance
(R)-1-Phenylpropylamine should be classified in the hazard category 3.
Currently, there is no
information available to cover this endpoint.
the available data for rac-1 -Phenyl-propylamine (CAS 2941-20-0, read
across) and (S)-1 -Phenyl-propylamine (CAS 3789-59-1, read across),
(R)-1-Phenyl-propylamine is subject to C&L:
to Regulation 1272/2008/EC: acute oral tox. 3, H301 (toxic)
to Directive 67/548/EEC: acute oral tox.: R22 (harmful)
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