Precedenti/Esito

Precedenti/Esito

Precedenti/Esito

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

There are currently no ongoing consultations.
 
Zinc bis[bis(dodecylphenyl)] bis(dithiophosphate) 259-048-8 54261-67-5
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts (EC 270-608-0) "Testing proposed according to a plan for the ZDDP category.“
04/10/2018
04/10/2018
19/11/2018
19/11/2018


Details
2-(2-Vinyloxyethoxy)ethyl acrylate 451-690-9 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
20/12/2017
20/12/2017
05/02/2018
05/02/2018
Details
Melamine 203-615-4 108-78-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 17/05/2016 01/07/2016 Details
Fatty acids, C18-unsatd., dimers, reaction products with polyethylenepolyamines 614-452-7 68410-23-1
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Details
Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine 500-191-5 -
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
28/02/2018
28/02/2018
16/04/2018
16/04/2018
Details
2,2'-[OXYBIS(METHYLENE)]BIS[2-ETHYLPROPANE-1,3-DIOL] 245-509-0 23235-61-2
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
29/04/2016
29/04/2016
13/06/2016
13/06/2016
Details
O,O,O-triphenyl phosphorothioate 209-909-9 597-82-0 Sub-chronic toxicity (90-day): oral 16/12/2016 30/01/2017 Details
COBALT DICHLORIDE 231-589-4 7646-79-9
Reproductive toxicity (extended one-generation reproductive toxicity study)

Reproductive toxicity (pre-natal developmental toxicity)
29/04/2016
29/04/2016
13/06/2016
13/06/2016
Details
cobalt dichloride 231-589-4 7646-79-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
18/07/2016
18/07/2016
01/09/2016
01/09/2016


Details
sodium 1H-benzotriazolide 239-269-6 15217-42-2 Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 1H-Benzotriazole (EC 202-394-1) 16/12/2016 30/01/2017 Details
[3-(2,3-epoxypropoxy)propyl]diethoxymethylsilane 220-780-8 2897-60-1 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 16/12/2016 30/01/2017 Details
tris[2-[2-(2-methoxyethoxy)ethoxy]ethyl] orthoborate 250-418-4 30989-05-0
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
29/04/2016
29/04/2016
13/06/2016
13/06/2016
Details
Reaction mass of C18 (unsatd.) fatty acid amides/esters of diethanolamine, C16-18 (even-numbered) fatty amine (..) 943-172-0 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
17/05/2016
17/05/2016
17/05/2016
01/07/2016
01/07/2016
01/07/2016
Details
Methylene-bis-4,1-(N-phenylene-N'-butylurea) 416-600-4 - Bioaccumulation aquatic / sediment 17/05/2016 01/07/2016 Details
Reaction products of a polyol of pentaerythritol and propylene oxide, epichlorohydrin and hydrogen sulfide 615-735-8 72244-98-5
Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: Testing proposal is based on concern identified by the registrant
Reproductive toxicity (pre-natal developmental toxicity)
11/11/2016
11/11/2016
03/01/2017
03/01/2017
Details
1,2,4,5,7,8-Hexoxonane, 3,6,9-trimethyl-, 3,6,9-tris(Ethyl and Propyl) derivatives - - Sub-chronic toxicity (90-day): oral 30/06/2016 15/08/2016 Details
Sodium dihydrogenorthophosphate 231-449-2 7558-80-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2016 17/10/2016 Details
boron orthophosphate - 13308-51-5 Reproductive toxicity (pre-natal developmental toxicity) 30/06/2016 15/08/2016 Details
Disodium; 4-Amino-3-{4-[4-(2,4-diamino-phenylazo)-benzenesulfonylamino]-phenylazo}-5-hydroxy-6-phenylazo-naphthalene-2,7-disulfonate 605-104-5 157577-99-6 Genetic toxicity in vivo 26/08/2021 11/10/2021 Details
platinum(IV) nitrate/nitric acid solution 432-400-1 - Genetic toxicity in vivo 26/08/2021 11/10/2021 Details
2-(2-Ethoxyethoxy)-2-methylpropanee 257-196-8 51422-54-9 Sub-chronic toxicity (90 day): inhalation Reproductive toxicity (pre-natal developmental toxicity) 03/02/2016 21/03/2016 Details
triethoxy(3-isocyanatopropyl)silane 246-467-6 24801-88-5 Genetic toxicity in vivo

Note: testing proposed with 3-(Trimethoxysilyl)propyl isocyanate (EC 239-415-9)
03/02/2016 21/03/2016 Details
O,O,O-triphenyl phosphorothioate 209-909-9 597-82-0 Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: Testing proposal is based on concern identified by the registrant.” 03/02/2016 21/03/2016 Details
2,2'-dimethyl-2,2'-azodipropiononitrile 201-132-3 78-67-1 Reproductive toxicity (pre-natal developmental toxicity) 03/02/2016 21/03/2016 Details
Butyl (dialkyloxy(dibutoxyphosphoryloxy))titanium(trialkyloxy)titanium phosphate 401-100-0 - Sub-chronic toxicity (90-day): oral 27/05/2019 11/07/2019 Details
N-{2-[(phenylcarbamoyl)amino]phenyl}benzenesulfonamide 806-543-7 215917-77-4 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant 30/11/2015 14/01/2016 Details
2,2'-(C16-18 (evennumbered, C18 unsaturated) alkyl imino) diethanol 620-540-6 1218787-32-6 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with 2,2'-(Octadec-9-enylimino) bisethanol, CAS No 25307-17-9 14/03/2016 28/04/2016 Details
Ethanol, 2,2'-iminobis-, N-C12-18-alkyl derivs. 276-014-8 71786-60-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/06/2019 09/08/2019 Details
1-(4-(ACETYLOXY)-3-((ACETYLOXY)METHYL)PHENYL)ETHANONE 921-042-4 - Genetic toxicity in vivo 25/05/2020 09/07/2020 Details
N,N'-dimethyldiphenylthiuram disulphide 234-196-6 10591-84-1
Reproductive toxicity (pre-natal developmental toxicity)
Sub-chronic toxicity (90-day): oral
16/08/2019
16/08/2019
30/09/2019
30/09/2019
Details
N,N''-propane-1,3-diylbis[N'-octadecylurea 252-667-4 35674-65-8 Sub-chronic toxicity (90-day): oral Reproductive toxicity (pre-natal developmental toxicity) 29/03/2016 13/05/2016 Details
Disodium [2,4-dihydro-4-[(2-hydroxy-5-nitrophenyl)azo]-5-methyl-2-phenyl-3H-pyrazol-3-onato(2-)][3-hydroxy-4-[(2-hydroxy-1-naphthyl)azo]-7-nitronaphthalene-1-sulphonato(3-)]chromate(2-) 274-490-1 70236-60-1 Genetic toxicity in vivo 21/10/2021 07/12/2021 Details
2,7-naphthalenedisulfonic acid, 4-amino-5-hydroxy-, diazotized, coupled with diazotized 2-amino-4,6-dinitrophenol, diazotized 4-nitrobenzenamine and resorcinol, sodium salts 232-380-0 8011-86-7 Genetic toxicity in vivo 21/10/2021 07/12/2021 Details
Potassium 3-sulphonatopropyl acrylate 250-465-0 31098-20-1 Genetic toxicity in vivo 17/06/2020 03/08/2020 Details
2,6-di-tert-butylphenol 204-884-0 128-39-2 Bioaccumulation aquatic / sediment 04/12/2023 18/01/2024 Details
1,4-bis(2,3-epoxypropoxy)butane 219-371-7 2425-79-8 Reproductive toxicity (extended one-generation reproductive toxicity study)|| Note: testing proposed with Reaction products of hexane-1,6-diol with 2-(chloromethyl)oxirane (1:2) (EC 618-939-5) 23/03/2020 07/05/2020 Details
2,2-dimethylpropane-1,3-diyl dibenzoate 224-081-9 4196-89-8 Reproductive toxicity (pre-natal developmental toxicity) 29/02/2016 14/04/2016 Details
Dichloromethylbenzene 249-854-8 29797-40-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 22/06/2017 07/08/2017 Details
3-methyldecane; benzene; cyclooctane; nonane 941-364-9 - Reproductive toxicity (extended one-generation reproductive toxicity study) 05/07/2018 20/08/2018 Details
N,N-bis(2-ethylhexyl)-5-methyl-1H-benzotriazole-1-methylamine, N,N-bis(2-ethylhexyl)-4-methyl-1H-benzotriazole-1-methylamine, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-4-methyl-, 2H-Benzotriazole-2-methanamine, N,N-bis(2-ethylhexyl)-5-methyl-, 1H-Benzotriazole-1-methanamine, N,N-bis(2-ethylhexyl)-6-methyl-(Mixture) 939-700-4 - Sub-chronic toxicity (90-day): oral 21/10/2019 05/12/2019 Details
Reaction products of diazotised 4,4-diaminodiphenylamine-2-sulfonic acid, subsequently coupled with 6-amino-4-hydroxynaphthalene-2-sulfonic acid, further diazotised and coupled with metaphenylendiamine, sodium salts 939-382-7 - Genetic toxicity in vivo 25/11/2021 10/01/2022 Details
2,2'-[hexane-1,6-diylbis(oxymethylene)]dioxirane 618-939-5 933999-84-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/10/2017 11/12/2017 Details
Amines, polyethylenepoly-, triethylenetetramine fraction,Triethylenetetramine linear, cyclic and branched 292-588-2 90640-66-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
01/09/2017
01/09/2017
16/10/2017
16/10/2017
Details
Amines, polyethylenepoly-, triethylenetetramine fraction 292-588-2 90640-66-7
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
22/11/2017
22/11/2017
08/01/2018
08/01/2018


Details
1,3-Benzenediamine, coupled with diazotized m-phenylenediamine, acetates 282-617-7 84281-74-3 Genetic toxicity in vivo 25/11/2021 10/01/2022 Details
Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene 270-128-1 68411-46-1 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/10/2017 11/12/2017 Details
2,2'-(octadec-9-enylimino)bisethanol 246-807-3 25307-17-9 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017 Details
tert-dodecanethiol 246-619-1 25103-58-6 Long-term toxicity to fish 16/06/2022 01/08/2022 Details
2,6-dimethyloct-7-en-2-ol 242-362-4 18479-58-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017 Details
Terpineol 232-268-1 8000-41-7 Reproductive toxicity (extended one-generation reproductive toxicity study) 01/09/2017 16/10/2017 Details