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Precedenti/Esito

Precedenti/Esito

This page provides the list of testing proposal consultations for which the deadline for comments has passed. ECHA addresses all third-party contributions in the dossier evaluation decisions addressed to the registrant.

Further instructions

To see if testing proposals submitted by registrants, and for which ECHA has held a third-party consultation, were subsequently withdrawn, please consult the table below. First, follow the link to the related aggregated registration dossier (if it is already published). There you can review the details of the testing proposed and other information on the substance that is subject to the testing proposal. The admissibility of any testing proposal will be concluded only after the third party consultation. Later during the testing proposal examination process, you may check the same section in the disseminated dossier to see if a testing proposal previously present has been withdrawn. The reasons for withdrawal may be that the registrant has reviewed their assessment or has taken into account the third-party comments provided to ECHA and communicated to them.

 
2,4,7,9-tetramethyl-4,7-decanediol 451-160-7 17913-76-7
Long-term toxicity to fish
"|| Note: testing proposed with 2,4,7,9-tetramethyldec-5-yne-4,7-diol (EC 204-809-1, CAS 126-86-3)
Reproductive toxicity (pre-natal developmental toxicity)
17/09/2019
17/09/2019
01/11/2019
01/11/2019
Fatty acids, C18-unsatd., dimers, oligomeric reaction products with triethylenetetramine 500-290-3 103758-99-2
Sub-chronic toxicity (90-day): oral
|| Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine (CAS 68082-29-1; EC 500-191-5)
Reproductive toxicity (pre-natal developmental toxicity)
|| Note: testing proposed with Fatty acids, C18-unsatd., dimers, oligomeric reaction products with tall-oil fatty acids and triethylenetetramine (CAS 68082-29-1; EC 500-191-5)
17/09/2019
17/09/2019
01/11/2019
01/11/2019
tetrasodium 7-[(E)-2-[2-(carbamoylamino)-4-{[4-chloro-6-({4-[2-(sulfooxy)ethanesulfonyl]phenyl}amino)-1,3,5-triazin-2-yl]amino}phenyl]diazen-1-yl]naphthalene-1,3,6-trisulfonate 474-870-9 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
17/09/2019
17/09/2019
01/11/2019
01/11/2019
1-aminopropan-2-ol 201-162-7 78-96-6 Reproductive toxicity (pre-natal developmental toxicity) 17/09/2019 01/11/2019
2,2'-(cyclohexylimino)bisethanol 224-809-5 4500-29-2 Reproductive toxicity (pre-natal developmental toxicity) 17/09/2019 01/11/2019
Butanoic acid, 4-amino-4-oxo-2(or 3)-sulfo-,N-(C16-C18 (even numbered), C18 unsaturated alkyl)), disodium salts 939-691-7 - Reproductive toxicity (pre-natal developmental toxicity) 17/09/2019 01/11/2019
Hydroxycyclohexyl phenyl ketone 213-426-9 947-19-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 17/09/2019 01/11/2019
Benzene, diethenyl- and Benzene, ethenylethyl- 910-757-7 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
16/08/2019
16/08/2019
30/09/2019
30/09/2019
N,N'-dimethyldiphenylthiuram disulphide 234-196-6 10591-84-1
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
16/08/2019
16/08/2019
30/09/2019
30/09/2019
Reaction mass of 1,3-Propanediol, 2-(hydroxymethyl)-2-[(methoxymethoxy)methyl]- and 1,3-dioxane-5,5-dimethanol 911-819-6 -
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
16/08/2019
16/08/2019
30/09/2019
30/09/2019
Sodium diisobutyldithiophosphinate 236-419-2 13360-78-6
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity) with Rat
24/07/2019
24/07/2019
09/09/2019
09/09/2019
1,3,5-tris[[4-tert-butyl-3-hydroxy-2,6-xylyl]methyl]-1,3,5-triazine-2,4,6(1H,3H,5H)-trione 254-996-9 40601-76-1 Reproductive toxicity (pre-natal developmental toxicity) with Rat 24/07/2019 09/09/2019
4-fluoro-1,3-dioxolan-2-one 483-360-5 114435-02-8 Genetic toxicity in vivo || Note: Testing proposal is based on concern identified by the registrant. 24/07/2019 09/09/2019
Bis(2-chloroethyl) 3,3'-[(2,5-dimethyl-p-phenylene)bis[iminocarbonyl(2-hydroxy-1,3-naphthylene)azo]]di-p-toluate 269-507-4 68259-05-2 Sub-chronic toxicity (90 day): inhalation || Note: Testing proposal is based on concern identified by the registrant 24/07/2019 09/09/2019
Heptanoic acid 203-838-7 111-14-8 Reproductive toxicity (extended one-generation reproductive toxicity study) 24/07/2019 09/09/2019
Reaction mass of trans-Cyclohexadecen-8-one, cis-Cyclohexadecen-8-one, trans-Cyclohexadecen-7-one, cis-Cyclohexadecen-7-one 448-300-4 88642-03-9 Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant. 24/07/2019 09/09/2019
Sodium dihydrogenorthophosphate 231-449-2 7558-80-7 Sub-chronic toxicity (90-day): oral 24/07/2019 09/09/2019
Sophorolipids: fermentation products of glucose and fatty acids, C18 (unsaturated), glycerol esters with yeast Candida Bombicola, partially hydrolysed 941-809-7 - Reproductive toxicity (pre-natal developmental toxicity) || Note: Testing proposal is based on concern identified by the registrant. 24/07/2019 09/09/2019
Fatty acids, C12-14, α-sulfo, disodium salts 942-523-5 -
Long-term toxicity to fish (OECD 212 – Registrant’s preference)
Sub-chronic toxicity (90-day): oral on rodents
Reproductive toxicity (pre-natal developmental toxicity) on rodents
25/06/2019
25/06/2019
25/06/2019
09/08/2019
09/08/2019
09/08/2019
Asphalt 232-490-9 8052-42-4 Reproductive toxicity (extended one-generation reproductive toxicity study)

[note whilst the registrant has selected the drop down of a RaX TPE – it is not a RaX TPE – registered substance is being tested]”
25/06/2019 09/08/2019
Asphalt, oxidized 265-196-4 64742-93-4 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/06/2019 09/08/2019
Benzyltoluene 248-654-8 27776-01-8 Long-term toxicity to fish (OECD 210) 25/06/2019 09/08/2019
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide 229-782-3 6731-36-8 Bioaccumulation aquatic / sediment 25/06/2019 09/08/2019
Ethanol, 2,2'-iminobis-, N-C12-18-alkyl derivs. 276-014-8 71786-60-2 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/06/2019 09/08/2019
Hexamethyldisiloxane 203-492-7 107-46-0 Reproductive toxicity (pre-natal developmental toxicity) with the rabbit via inhalation 25/06/2019 09/08/2019
pentasodium 5-{[4-chloro-6-({4-[2-(sulfooxy)ethanesulfonyl]phenyl}amino)-1,3,5-triazin-2-yl]amino}-3-[2-(1,5-disulfonaphthalen-2-yl)diazen-1-yl]-4-hydroxynaphthalene-2,7-disulfonate 402-420-3 89157-03-9 Sub-chronic toxicity (90-day): oral 25/06/2019 09/08/2019
Residues (petroleum), thermal cracked vacuum 295-518-9 062-05-0 Reproductive toxicity (extended one-generation reproductive toxicity study) || Note: testing proposed with Asphalt (CAS 8052-42-4) 25/06/2019 09/08/2019
Residues (petroleum), vacuum 265-057-8 64741-56-6 Reproductive toxicity (extended one-generation reproductive toxicity study) 25/06/2019 09/08/2019
Strontium oxide 215-219-9 1314-11-0 Reproductive toxicity (pre-natal developmental toxicity) 25/06/2019 09/08/2019
Triisotridecyl phosphite 278-758-9 77745-66-5 Sub-chronic toxicity (90-day): oral 25/06/2019 09/08/2019
Reaction mass of Octadecanamide, 12-hydroxy-N-[2-[(1-oxodecyl)amino]ethyl]- and N,N'-ethane-1,2-diylbis(12-hydroxyoctadecan-1-amide) and Decanamide, N,N'-1,2-ethanediylbis- 907-495-0 -
Reproductive toxicity (pre-natal developmental toxicity): in rat and rabbit
Sub-chronic toxicity (90 day): inhalation
Reproductive toxicity (extended one-generation reproductive toxicity study)
27/05/2019
27/05/2019
27/05/2019
11/07/2019
11/07/2019
11/07/2019
Benzene, 1,1'-oxybis-, tetrapropylene derivatives, sulfonated, sodium salts 601-601-6 119345-04-9
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity) with the Rabbit
27/05/2019
27/05/2019
11/07/2019
11/07/2019
Lithium bis(oxalato)borate 456-990-3 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
27/05/2019
27/05/2019
11/07/2019
11/07/2019
Methylphosphonic acid 213-607-2 993-13-5
Sub-chronic toxicity (90-day): oral || Note: testing proposed with Methylphosphonic acid, compound with amidinourea (1:1) (EC 282-758-4)
Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with Methylphosphonic acid, compound with amidinourea (1:1) (EC 282-758-4)
27/05/2019
27/05/2019
11/07/2019
11/07/2019
tri{[(2s)-1-ethoxy-1-oxopropan-2-yl]oxy}(vinyl)silane 701-301-6 -
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (pre-natal developmental toxicity)
27/05/2019
27/05/2019
11/07/2019
11/07/2019
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide 246-678-3 25155-25-3 Reproductive toxicity (extended one-generation reproductive toxicity study) 27/05/2019 11/07/2019
Alcohols, C11-14-iso-, C13-rich 271-235-6 68526-86-3 Reproductive toxicity (pre-natal developmental toxicity) 27/05/2019 11/07/2019
Butyl (dialkyloxy(dibutoxyphosphoryloxy))titanium(trialkyloxy)titanium phosphate 401-100-0 - Sub-chronic toxicity (90-day): oral 27/05/2019 11/07/2019
Furan-2,5-dicarboxylic acid 221-800-8 3238-40-2 Reproductive toxicity (pre-natal developmental toxicity) 27/05/2019 11/07/2019
Hexanal 200-624-5 66-25-1 Genetic toxicity in vivo “|| Note: Testing proposal is based on concern identified by the registrant.” 27/05/2019 11/07/2019
Reaction mass of 2,2'-[(4-methylphenyl)imino]bisethanol and Ethanol 2-[[2-(2-hydroxyethoxy)ethyl](4-methylphenyl)amino]- 911-490-9 - Sub-chronic toxicity (90-day): oral 27/05/2019 11/07/2019
Reaction mass of 2-(2-(2-butoxyethoxy)ethoxy)ethanol and 3,6,9,12-tetraoxahexadecan-1-ol 907-996-4 - Reproductive toxicity (pre-natal developmental toxicity) || Note: testing proposed with 2-(2-(2-butoxyethoxy)ethoxy)ethanol (EC 205-592-6) 27/05/2019 11/07/2019
Reaction Mass of Benzyl (1R,1S) 2,2,4-trimethyl-1-[(2-methylpropanoyl)oxy]pentan-3-yl benzene-1,2-dicarboxylate and Benzyl (3R,3S) 2,2,4-trimethyl-3-[(2-methylpropanoyl)oxy]pentyl benzene-1,2-dicarboxylate 701-008-3 - Reproductive toxicity (extended one-generation reproductive toxicity study) 27/05/2019 11/07/2019
Sodium hydroxymethanesulphinate 205-739-4 149-44-0 Reproductive toxicity (pre-natal developmental toxicity) 27/05/2019 11/07/2019
Isobutyric acid, monoester with 2,2,4-trimethylpentane-1,3-diol 246-771-9 25265-77-4
Sub-chronic toxicity (90-day): oral
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/04/2019
26/04/2019
26/04/2019
10/06/2019
10/06/2019
10/06/2019
Zinc, O,O-mixed (iso-Bu), (iso-Pr), (pentyl) phosphorodithioate 820-225-5 101747-77-7
Sub-chronic toxicity (90-day): oral “|| Note: testing proposed with [Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts] (EC 270-608-0)
Reproductive toxicity (extended one-generation reproductive toxicity study) “|| Note: testing proposed with [Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts] (EC 270-608-0)
Reproductive toxicity (pre-natal developmental toxicity) “|| Note: testing proposed with [Phosphorodithioic acid, mixed O,O-bis(iso-Bu and pentyl) esters, zinc salts] (EC 270-608-0)
26/04/2019
26/04/2019
26/04/2019
10/06/2019
10/06/2019
10/06/2019
3-(trimethoxysilyl)propylamine 237-511-5 13822-56-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/04/2019
26/04/2019
10/06/2019
10/06/2019
Biphenyl-4,4'-diol 202-200-5 92-88-6
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/04/2019
26/04/2019
10/06/2019
10/06/2019
Ethylenediamine, propoxylated 500-035-6 25214-63-5
Reproductive toxicity (extended one-generation reproductive toxicity study)
Reproductive toxicity (pre-natal developmental toxicity)
26/04/2019
26/04/2019
10/06/2019
10/06/2019
2-Propyn-1-ol, reaction product with 1-2.5 moles of oxirane 941-793-1 - Reproductive toxicity (pre-natal developmental toxicity) 26/04/2019 10/06/2019



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