Registration Dossier
Registration Dossier
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EC number: 246-376-1 | CAS number: 24634-61-5
Endpoint summary
Administrative data
Description of key information
In short-term to subchronic oral studies, Sorbic Acid and Potassium Sorbate were pratically non-toxic in rats and dogs at concentrations up to 10 and 2% respectively.
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Dose descriptor:
- NOAEL
- 6 792 mg/kg bw/day
- Study duration:
- subchronic
- Species:
- rat
Additional information
In short-term to subchronic oral studies, Sorbic Acid and Potassium Sorbate were pratically non-toxic in rats and dogs at concentrations up to 10 and 2% respectively .Studies failed to elicit any toxic response, based on the absence of any specific abnormalities upon gross and histopathological examination of target organs.
The extrapolation from sorbic acid to potassium sorbate is considered not to be restricted in any way, since the determination of potential repeated dose toxicity is the "sorbate" anion.
Justification for classification or non-classification
According to regulation (EC) No 1272/2008, sorbic acid and potassium sorbate are not classified for STOT RE.
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