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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Administrative data

Link to relevant study record(s)

Description of key information

The following study was provided as the key study for the endpoint toxicity to microorganisms:
Clarke, N (2010) ASSESSMENT OF THE INHIBITORY EFFECT ON THE RESPIRATION OF ACTIVATED SEWAGE SLUDGE. Testing laboratory: Harlan Laboratories Limited, Shardlow Business Park, Shardlow, Derbyshire, DE72 2GD, UK. Owner company: Organo Tin REACH Consortium, c/o ReachCentrum, Avenue E. Van Nieuwenhuyse 6, B-1160, Brussels, BELGIUM. Report No.: 3109/0040
The effect of the test item on the respiration of activated sewage sludge micro-organisms gave a 3-Hour EC50 of 190 mg/l. The No Observed Effect Concentration (NOEC) after 3 hours exposure was 12 mg/l.

Key value for chemical safety assessment

EC50 for microorganisms:
190 mg/L
EC10 or NOEC for microorganisms:
12 mg/L

Additional information

A reliability rating of 1 was assigned to the key study, Clarke (2010), according to the criteria of Klimisch, 1997 as the study was conducted in accordance with a recognised guideline (OECD 209) and GLP. The 3-Hour EC50 was reported to be 190 mg/l. The No Observed Effect Concentration (NOEC) after 3 hours exposure was 12 mg/l.