Registration Dossier
Registration Dossier
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EC number: 203-905-0 | CAS number: 111-76-2
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Pseudomonas putida. 16hr TT =700mg/l; 6hr EC10 ~ 540mg/L, EC20 ~ 1140mg/L
Uronema parduczi. 48hr TT=463mg/l
Chilomonas paramecium 48hr TT=911mg/l
Entosiphon sulcatum. 72hr TT = 7391mg/l
Hydrogenophaga pseudoflava, 14hr EC10 ~1380mg/L
Pseudomonas vacouverensis, 12hr EC10 ~955mg/L
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 463 mg/L
Additional information
A number of studies have been carried out to assess the toxicity of 2 -butoxyethanol to micro-organism using multiple species of protozoa and bacteria in fresh water. These studies that are reliable indicate that the substance may be slightly toxic to micro-organisms but all of species except one exhibited very similar sensitivity (with Entosiphon showing very low toxicity). The weight of evidence suggested that the substance is generally of low toxicity. Ciliated protozoa are acceptable as surrogates to predict the toxicity in a WWTP; Uronema meet this criteria (but not Entosiphon). The Uronema figure is therefore selected as the key parameter from which to predict the hazard to degradation of substances in waste water treatment plants.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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