Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
201-297-1
CAS no.:
80-62-6
Index number:
607-035-00-6
Molecular formula:
C5H8O2
SMILES:
COC(=O)C(C)=C
InChI:
InChI=1S/C5H8O2/c1-4(2)5(6)7-3/h1H2,2-3H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
27
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance is a highly flammable liquid and vapour, causes skin irritation, may cause an allergic skin reaction and may cause respiratory irritation.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance may be harmful if inhaled and is harmful to aquatic life.

Breakdown of all 4513 C&L notifications submitted to ECHA

Flam. Liq. 2 H225 Harmonised Classification
Skin Irrit. 2 H315 Harmonised Classification
STOT SE 3 H335 Harmonised Classification
Skin Sens. 1 H317 Harmonised Classification
Skin Sens. 1B H317
Acute Tox. 5 H333
Aquatic Acute 3 H402
STOT SE 3 H370
Eye Irrit. 2 H319
Acute Tox. 3 H301
STOT RE 1 H372
Acute Tox. 4 H302
Repr. 2 H361
Aquatic Chronic 3 H412
Resp. Sens. 1 H334
https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/more.png 0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://www.echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • Ss
Officially recognised in the EU as Skin sensitising ( Harmonised C&L).
  • Ss
There is broad agreement in that a majority of data submitters agree this substance is Skin sensitising (100% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 156 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Substance included in the Community Rolling Action Plan (CoRAP).
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Industrial accident prevention and reporting requirements have been established for this substance.
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 100 000 to < 1 000 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

ECHA has no public registered data indicating whether or in which chemical products the substance might be used.

Other release to the environment of this substance is likely to occur from: outdoor use and indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners).

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, industrial spraying, transfer of substance into small containers, hand mixing with intimate contact only with personal protective equipment available, heat / pressure transfer fluids in closed systems, the low energy manipulation of substances bound in materials or articles, open transfer and processing with minerals/metals at elevated temperature, high energy work-up of substances bound in materials or articles (e.g. hot rolling/forming, grinding, mechanical cutting, drilling or sanding) and handling of solid inorganic substances (e.g. ores and raw metal oxides, packaging/mixing/blending and weighing of metal powders).

Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in complex articles, with no release intended: electrical batteries and accumulators, vehicles and machinery, mechanical appliances and electrical/electronic products (e.g. computers, cameras, lamps, refrigerators, washing machines). This substance can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones), leather (e.g. gloves, shoes, purses, furniture), fabrics, textiles and apparel (e.g. clothing, mattress, curtains or carpets, textile toys), paper (e.g. tissues, feminine hygiene products, nappies, books, magazines, wallpaper), rubber (e.g. tyres, shoes, toys), stone, plaster, cement, glass or ceramic (e.g. dishes, pots/pans, food storage containers, construction and isolation material), wood (e.g. floors, furniture, toys) and metal (e.g. cutlery, pots, toys, jewellery).

This substance is used in the following products: polymers, coating products, inks and toners, fillers, putties, plasters, modelling clay, laboratory chemicals and water treatment chemicals.

This substance is used in the following areas: building & construction work, printing and recorded media reproduction and scientific research and development. This substance is used for the manufacture of: plastic products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, mixing in open batch processes and treatment of articles by dipping and pouring.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following products: polymers.

This substance is used in the following activities or processes at workplace: transfer of chemicals, transfer of substance into small containers, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes and hand mixing with intimate contact only with personal protective equipment available.

Release to the environment of this substance can occur from industrial use: formulation of mixtures and formulation in materials.

This substance is used in the following products: polymers.

This substance is used in the following areas: mining and municipal supply (e.g. electricity, steam, gas, water) and sewage treatment. This substance is used for the manufacture of: chemicals, plastic products, electrical, electronic and optical equipment, machinery and vehicles, mineral products (e.g. plasters, cement) and metals.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, mixing in open batch processes, transfer of substance into small containers, batch processing in synthesis or formulation with opportunity for exposure and laboratory work.

Release to the environment of this substance can occur from industrial use: for thermoplastic manufacture, as processing aid, in processing aids at industrial sites, as processing aid, of substances in closed systems with minimal release, as an intermediate step in further manufacturing of another substance (use of intermediates) and in the production of articles.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, batch processing in synthesis or formulation with opportunity for exposure, mixing in open batch processes, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance, in processing aids at industrial sites, in the production of articles, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, for thermoplastic manufacture, as processing aid and of substances in closed systems with minimal release.

Precautions for using this substance have been recommended by its registrants under REACH, as follows:

Prevention statements

When handling this substance: ground and bond container and receiving equipment; take actions to prevent static discharges; contaminated work clothing should not be allowed out of the workplace; keep away from heat, sparks, open flames and/or hot surfaces – No smoking; use only outdoors or in a well-ventilated area; keep container tightly closed; use explosion-proof equipment (electrical/ventilating/lighting/etc.); avoid release to the environment; use non-sparking tools; wash parts of the body (as specified by manufacturer/supplier)in contact with substance thoroughly after handling; wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier; avoid breathing the dust, fume, gas, mist, vapours or spray.

Response statements

In case of incident: Take off contaminated clothing and wash it before reuse. Call a poison center or doctor/physician if you feel unwell. If skin irritation or a rash occurs: get medical advice/attention. If on skin (or hair): take off immediately all contaminated clothing. Rinse skin with water or shower. If inhaled: remove victim to fresh air and keep at rest in a position comfortable for breathing. In case of fire: Use (measures specified by manufacturer/supplier) for extinction. If on skin: wash with soap and water.

Storage statements

Store this substance in a well-ventilated place and Keeping it cool; locked up.

Disposal statements

The substance must be disposed in accordance with local/regional/national/international regulation.

Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • 3M Belgium BVBA/SPRL, Hermeslaan 7 1831 Diegem Belgium
  • 3M Deutschland GmbH, Carl-Schurz-Strasse 1 41453 Neuss Germany
  • 3M France SAS, 1 Parvis de l'Innovation CS 20203 95006 Cergy-Pontoise Cedex France
  • Afton Chemical S.R.L. (Woluwe), Alma Court Lenneke Marelaan, 8 B-1932 St-Stevens-Woluwe Belgium
  • AKZO Nobel Car Refinishes B.V., Rijksstraatweg 31 2170 BA Sassenheim Netherlands
  • Allnex Belgium NV/SA OR1, Anderlechtstraat 33 1620 Drogenbos Belgium
  • Alpha OR KMC, Merseyweg 16 PO Box 1222, 3180AE Rozenburg ZH, 3197 KG Botlek RT Zuid Holland Netherlands
  • Alpha OR LI Inc, Merseyweg 16, PO Box 1222, 3180AE Rozenburg ZH, 3197 KG Botlek Rt Zuid Holland Netherlands
  • Alpha OR LICC, Merseyweg 16, PO Box 1222, 3180AE Rozenburg ZH, 3197 KG Botlek Rt Zuid Holland Netherlands
  • Alpha OR LIUK, Merseyweg 16, PO Box 1222, 3180AE Rozenburg ZH, 3197 KG Botlek Rotterdam Zuid Holland Netherlands
  • Alpha OR MCC Huizhou China , Merseyweg 16, PO Box 1222, 3180AE Rozenburg ZH, 3197 KG Botlek Rotterdam Zuid Holland Netherlands
  • Alpha OR MCC Japan, Merseyweg 16, PO Box 1222, 3180AE Rozenburg ZH, 3197 KG Botlek Rotterdam Zuid Holland Netherlands
  • Alpha OR MCC Korea, Merseyweg 16, PO Box 1222, 3180AE Rozenburg ZH, 3197 KG Botlek Rotterdam Zuid Holland Netherlands
  • Alpha OR MCC SAMAC, Merseyweg 16, PO Box 1222, 3180AE Rozenburg ZH, 3197 KG Botlek Rotterdam Zuid Holland Netherlands
  • Alpha OR MCC Thailand, Merseyweg 16, PO Box 1222, 3180AE Rozenburg ZH, 3197 KG Botlek Rotterdam Zuid Holland Netherlands
  • ALTUGLAS S.R.L., Via Pregnana 63 CAP 20017 Milan RHO Italy
  • ARKEMA B.V., headquarters Postbus 6030 3196 XH Vondelingenplaat Rotterdam Netherlands
  • ARKEMA PHOTOCURES, 420 rue d'Estienne d'Orves 92700 Colombes France
  • Arpadis Benelux NV, Desguinlei 88A 2018 Antwerp Belgium
  • Ashland Services BV (0311), Noordweg 9 3336 LH Zwijndrecht Netherlands
  • Avery Dennison Materials Europe BV, Willem Einthovenstraat 11 2342 BH Oegstgeest Zuid-Holland Netherlands
  • Axalta Coating Systems Germany GmbH & Co. KG, Christbusch 25 42285 Wuppertal Germany
  • B.I.G. - OR18190, Technische Schoolstraat 43a 2440 Geel Belgium
  • B.I.G. - OR634, Technische Schoolstraat 43A 2440 Geel Belgium
  • B.I.G. - OR646, Technische Schoolstraat 43A 2440 Geel Belgium
  • BASF Coatings GmbH, Glasuritstrasse 1 Postfach 6123 48136 Münster Nordrhein-Westfalen Germany
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • BorsodChem Zrt. - OR, Bolyai ter 1. H-3700 Kazincbarcika Hungary
  • Cambridge Environmental Assessments, part of RSK ADAS Europe (Ireland) Ltd, Office Suite B, Bluebell Business Centre Old Naas Rd D12XV7K Dublin Ireland
  • Caplinq Europe B.V., Industrieweg 15E 1566JN Assendelft - Netherlands
  • Celanese Europe BV, The New Atrium Strawinskylaan 3105 1077 ZX Amsterdam Netherlands
  • CellMark Deutschland GmbH, Hamborner Straße 53 D - 40547 Düsseldorf Germany Germany
  • Chemetall GmbH, Trakehner Str. 3 60487 Frankfurt Germany
  • Chemical Inspection & Regulation Service Limited, Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77, D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • Chemical Inspection & Regulation Service Limited, Regus Harcourt Centre D02 HW77 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77, Dublin, Ireland D02 Dublin Ireland
  • CHEMICAL INSPECTION & REGULATION SERVICE LIMITED, Room 002, Regus Harcourt Centre D02 HW77 D02 Dublin Ireland
  • Chemservice S.A. (H5P7), 13, Fausermillen 6689 Mertert Luxembourg
  • COSMO GROUP Sp. z o.o. Sp. k., Jasielska 10a 60-476 Poznań Poland
  • COVANCE CLINICAL DEVELOPMENT SA 017, Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain
  • Covance Clinical Development SA 023, Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain
  • COVANCE CLINICAL DEVELOPMENT SA 060, Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5-5 Planta 28050 Madrid Spain
  • COVANCE CLINICAL DEVELOPMENT SA 087, Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain
  • Covance Clinical Development SA 129, Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5-5 Planta 28050 Madrid Spain
  • Covance Clinical Development SA 155, Parque Empresarial Las Tablas, Edifico 1 Calle Federico Mompou, 5 - 5 Planta 28050 Madrid Spain
  • COVANCE CLINICAL DEVELOPMENT SA 156, Parque Empresarial Las Tablas, Edificio 1 Calle Federico Mompou, 5 – 5 Planta 28050 Madrid Spain
  • Covestro Deutschland AG, Kaiser-Wilhelm-Allee 60 51373 Leverkusen Germany
  • CS Regulatory IRL Ltd 1L-13, Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland
  • CS Regulatory IRL Ltd 1L-8, Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland
  • CS Regulatory IRL Ltd 1L-9, Alexandra House The Sweepstakes D04 C7H2 Dublin Ballsbridge Ireland
  • DKSH Italia S.r.l., Via Salvatore Rosa, 14 20156 Milano Italy
  • Dow Belgium B.V.B.A., Grotesteenweg 214 B-2600 Antwerpen (Berchem) Belgium Belgium
  • DOW BENELUX B.V., Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-10, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-11, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-13, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-5, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-6, Postbus 48 NL-4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-7, Postbus 48 NL-4530 AA Terneuzen Netherlands
  • Dow Benelux B.V. OR-20, Postbus 48 4530 AA Terneuzen Netherlands
  • Dow Benelux B.V. OR-51, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-52, Postbus 48 4530 AA Terneuzen Netherlands
  • DOW BENELUX B.V. OR-53, Postbus 48 4530 AA Terneuzen Netherlands
  • Dow France SAS, 23 Avenue Jules Rimet 93200 La Plaine Saint Denis France
  • Dow Silicones Belgium SPRL, Rue Jules Bordet Zone industrielle C 7180 Seneffe Belgium
  • Du Pont de Nemours (Deutschland) GmbH, Hugenottenallee 175 D-63263 Neu-Isenburg Hesse Germany
  • ECEM, Hogehilweg 18 1101CD Amsterdam Noord Holland Netherlands
  • Elementis Minerals B.V., Kajuitweg 8 1041AR Amsterdam Netherlands
  • ELGA EUROPE SRL, Via della Merlata, 8 20014 NERVIANO MILANO Italy
  • Evonik Operations GmbH, Rellinghauser Straße 1-11 45128 Essen Germany
  • Evonik Operations GmbH - ME01, Rellinghauser Straße 1-11 45128 Essen Germany
  • Evonik Operations GmbH - OA01, Rellinghauser Straße 1 – 11 45128 Essen Germany
  • Evonik Operations GmbH - OA02, Rellinghauser Straße 1 – 11 45128 Essen Germany
  • Evonik Operations GmbH - OA04, Rellinghauser Straße 1 – 11 45128 Essen Germany
  • Experien Chemical Services (Ireland) Limited, Unit 3D North Point House North Point Business Park, New Mallow Road T23 AT2P Cork Ireland
  • FujiFilm Manufacturing Europe BV, Oudenstaart 1 5047 TK Tilburg Netherlands
  • Galata Chemicals GmbH, Chemiestrasse 22 68623 Lampertheim 06 Germany
  • Gantrade Europe BVBA, Blokhuisstraat 47 J 2800 Mechelen Belgium
  • Henkel Global Supply Chain B.V., Gustav Mahlerlaan 2970 1081 LA Amsterdam Netherlands
  • HH Compliance Ltd, Rubicon Centre C.I.T. Campus T12 Y275 Bishopstown Cork Ireland
  • INEOS Styrolution Europe GmbH, Mainzer Landstrasse 50 60325 Frankfurt am Main Germany
  • International Farg AB, Box 44 SE 424 22 Angered Sweden
  • Intertek Deutschland GmbH 1, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
  • Intertek Deutschland GmbH 40, Stangenstrasse 1 70771 Leinfelden-Echterdingen Germany
  • Intertek Deutschland GmbH ITCI, Stangenstr. 1 70771 Leinfelden-Echterdingen Germany
  • ITW Performance Polymers, A Division of ITW Ireland, Bay 150 Shannon Industrial Estate V14 DF82 Shannon Co. Clare Ireland
  • KH Chemicals B.V., Scheepmakerij 260 3331 MB Zwijndrecht Netherlands
  • KTR Europe GmbH, Mergenthalerallee 77 65760 Eschborn Germany
  • Kuraray Europe GmbH, Philipp-Reis-Str. 4 65795 Hattersheim Germany
  • Lubrizol Advanced Materials Europe B.V.B.A, Nijverheidsstraat 30 2260 Westerlo-Oevel Belgium
  • Lubrizol Europe Coordination Center BVBA 01, Chaussee De Wavre, 1945 1945 Brussels Belgium
  • Lubrizol Europe Coordination Center BVBA 02 , Chaussee De Wavre 1945 Brussels Belgium
  • Lubrizol France SAS, 25 Quai de France 76100 ROUEN France
  • Mitsubishi Polyester Film GmbH, Kasteler Str. 45 65203 Wiesbaden Germany
  • Mitsui and Co. Deutschland G.M.B.H. Head Office (Düsseldorf), Herzogstrasse 15 D-40217 Düsseldorf Germany
  • Momentive Performance Materials GmbH, Chempark Building V7 51368 Leverkusen NRW Germany
  • NAM & NAM Europe GmbH, Emil-Figge-Str. 80 44227 Dortmund(054) Germany
  • Nouryon Surface Chemistry AB, Stenunge Allé S-44485 STENUNGSUND Sweden
  • Nouryon Surface Chemistry AB, Stenunge Allé 3 - S-44485 Stenungsund - Sweden
  • Novasol S.A., Mechelsesteenweg 455 1950 Kraainem Belgium
  • OMNOVA Solutions SAS (OR of OMNOVA Solutions Inc), 14 avenue des Tropiques ZA de Courtaboeuf 2, Villejust 91955 Courtaboeuf Cedex France
  • Only representative (No publishable name), null
  • Opes International BV, Overschiestraat 59 1062XD Amsterdam Netherlands
  • Panasonic Industrial Devices Slovakia s.r.o., Oravicka 616 02801 Trstena Slovakia
  • Performance Specialty Products Italy Srl , Via Pontaccio 10 20121 Milano Lombardia Italy
  • PetroChina International (Netherlands) Company B.V, Vasteland 78 HNK Rotterdam Scheepvaartkwartier 3011BN Rotterdam Netherlands
  • PPG Industries Italia Srl Società soggetta a direzione e coordinamento da parte di PPG Industries Inc., Via Serra, 1 15028 Quattordio Italy
  • REACH24H CONSULTING GROUP, Paramount Court, Corrig Road, Sandyford Dublin18 Dublin Ireland
  • REACHLaw Ltd, Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • REACHLaw Ltd., Vänrikinkuja 3 JK 21 02600 Espoo Finland
  • REACHLINKED OÜ, Ahtri tn 12 10151 Tallinn Estonia
  • Ricardo Nederland BV, Catharijnesingel 33 3511 GC Utrecht Netherlands
  • Roehm America LLC - ORR1, Deutsche-Telekom-Allee 9 64295 Darmstadt Germany
  • RSI ChemRep Europe Ltd (K010), 27-30 Merchants Quay Merchants House 8 Dublin Ireland
  • Röhm Chemical Shanghai OR-R4, Deutsche-Telekom-Allee 9 64295 Darmstadt Germany
  • Röhm GmbH, Deutsche-Telekom-Allee 9 64295 Darmstadt Germany
  • SABIC Innovative Plastics BV, Plasticslaan 1 4612 PX Bergen op Zoom Netherlands Netherlands
  • SABIC Petrochemicals B.V., Europaboulevard 1 6135 LD Sittard Limburg Netherlands
  • Sakata INX España S.A. (JP), C/ Mercaders 24-26. Pol.Ind.Riera de Caldes E-08184 Palau Solità i Plegamans Barcelona Spain
  • SCAS Europe S.A./N.V., Leonardo Da Vincilaan 19 B-1831 Diegem Belgium
  • SEAVIEW PROGRESS, Zi du Capitou - 85 rue Louis Lépine 83600 Fréjus France
  • Showa Denko Europe GmbH (SDK), Daimlerstrasse 19 86368 Gersthofen Germany
  • SHPP B.V., Plasticslaan 1 4612PX Bergen op Zoom Netherlands
  • Specialty Electronic Materials Netherlands BV OR-1, Baanhoekweg 22 3313 LA Dordrecht Netherlands
  • Specialty Products Poland sp. z o.o., ul. Postępu 17B 02-676 Warsaw Poland
  • SRL Dental GmbH, Giulinistr. 2 67065 Ludwigshafen Germany
  • Stadex Nederland BV as OR for Shandong, Boxbergerweg 119 7431PM Diepenveen Netherlands
  • Stahl Europe B.V., Sluisweg 10 5145PE Waalwijk Noord Brabant Netherlands
  • Stewardship Chemicals 28, Długosza 67 43-188 Orzesze Poland
  • Sun Chemical B.V., Leeuwenveldseweg 3-t 1382 LV Weesp Netherlands
  • Synthomer Trading Limited Dutch branch, Ijesselstraat 41 5347 KG Oss Netherlands
  • Synthomer Trading Limited Dutch Branch, Ijesselstraat 41 5437 KG Oss Netherlands
  • TramacoGmbH, Lise-Meitner-Allee 8 25411 Tornesch Germany
  • TSGE_2019-054, Im Fliegerhorst 12 38642 Goslar Germany
  • TÜV SÜD Iberia S.A.U. (052), Ronda Can Fatjó 13 08290 Cerdanyola del Vallès Barcelona Spain
  • UMCO GmbH, Georg-Wilhelm-Straße 187 21107 Hamburg Germany
  • Valspar b.v., Zuiveringweg 89 8243 PE Lelystad Netherlands
  • VAMP - TECH S.p.A., Via delle Industrie 10/12 20874 Busnago Italy
  • Wacker Chemie AG, Hanns-Seidel-Platz 4 81737 Muenchen Germany
  • [Confidential], [Confidential]
  • 3M United Kingdom Plc, 3M Centre, Cain Road RG12 8HT Bracknell - Berkshire United Kingdom
  • Du Pont (U.K.) Limited, London Road 4th Floor, Kings Court SG1 2NG Stevenage Hertfordshire United Kingdom
  • Henkel Italia Operations S.r.L., Via Amoretti 78 20157 Mailand Italy
  • HH Compliance Ltd, Rubicon Centre C.I.T. Campus T12 Y275 Bishopstown Cork Ireland
  • Sigma-Aldrich Company Limited, The Old Brickyard, New Road SP8 4XT Gillingham United Kingdom
  • Specialty Electronic Materials Netherlands BV, Baanhoekweg 22 3313 LA Dordrecht Netherlands
  • [Confidential], [Confidential]

Substance names and other identifiers

methacrylic acid, methyl ester
FCM and Articles Regulation, Annex I - Authorised Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use
methyl 2-methylprop-2-enoate
C&L Inventory
methyl 2-methylpropenoate
C&L Inventory
Methyl methacrylate
EC Inventory, C&L Inventory, REACH pre-registration, Other, Occupational Exposure Limits - 3rd list - Indicative OELVs
Methyl methacrylate
C&L Inventory, Substance Evaluation - CoRAP, REACH pre-registration, Other, Occupational Exposure Limits - 3rd list - Indicative OELVs
METHYL METHACRYLATE MONOMER, STABILIZED
Inland Transport of Dangerous Goods Directive, Annex III - ADN, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID
methyl methacrylate; methyl 2-methylprop-2-enoate; methyl 2-methylpropenoate
Aerosols Directive - Flammable Contents - Labelling Requirements, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
ester metylowy kwasu metakrylowego (pl)
C&L Inventory
metacrilato de metilo (es)
C&L Inventory
metacrilato de metilo (pt)
C&L Inventory
metacrilato di metile (it)
C&L Inventory
metakrylan metylu (pl)
C&L Inventory
Methyl 2-methylprop-2-enoat (de)
C&L Inventory
methyl-2-methylprop-2-enoát (cs)
C&L Inventory
methyl-2-methylpropenoát (cs)
C&L Inventory
Methyl-methacrylat (de)
C&L Inventory
methyl-methakrylát (cs)
C&L Inventory
methylmethacrylaat (nl)
C&L Inventory
methylmethacrylat (da)
C&L Inventory
metil 2-metilprop-2-enoat (ro)
C&L Inventory
metil 2-metilprop-2-enoat (sl)
C&L Inventory
metil 2-metilprop-2-enoato (it)
C&L Inventory
metil 2-metilprop-2-enoato (pt)
C&L Inventory
metil 2-metilprop-2-enoát (hu)
C&L Inventory
metil 2-metilpropenoat (ro)
C&L Inventory
metil 2-metilpropenoat (sl)
C&L Inventory
metil 2-metilpropenoato (pt)
C&L Inventory
metil 2-metilpropenoát (hu)
C&L Inventory
metil 2-metilpropenoāts (lv)
C&L Inventory
metil 2-metilpropenoāts-2 (lv)
C&L Inventory
metil metacrilat (ro)
C&L Inventory
metil metakrilat (sl)
C&L Inventory
metil-2-metil-2-propenoatas (lt)
C&L Inventory
metil-2-metil-prop-2-enoat (hr)
C&L Inventory
metil-2-metil-propenoat (hr)
C&L Inventory
metil-2-metilpropenoatas (lt)
C&L Inventory
metil-metacrilato (it)
C&L Inventory
metil-metakrilat (hr)
C&L Inventory
metil-metakrilát (hu)
C&L Inventory
metilmetakrilatas (lt)
C&L Inventory
metilmetakrilāts (lv)
C&L Inventory
metyl-2-metylprop-2-enoát (sk)
C&L Inventory
metyl-metakrylát (sk)
C&L Inventory
metylmetakrylat (no)
C&L Inventory
metylmetakrylat (sv)
C&L Inventory
Metyyli-2-metyyliprop-2-enoaatti (fi)
C&L Inventory
Metyyli-2-metyylipropenoaatti (fi)
C&L Inventory
Metyylimetakrylaatti (fi)
C&L Inventory
metüül-2-metüülprop-2-enaat (et)
C&L Inventory
metüül-2-metüülpropenaat (et)
C&L Inventory
Metüülmetakrülaat (et)
C&L Inventory
MMA (de)
C&L Inventory
méthacrylate de méthyle; 2-méthylprop-2-énoate de méthyle; 2-méthylpropénoate de méthyle (fr)
C&L Inventory
O-metyl-2-metylpropenoát (sk)
C&L Inventory
μεθακρυλικός μεθυλεστέρας (el)
C&L Inventory
мeтил-метакрилат (bg)
C&L Inventory
метил 2-метилпроп-2-еноат (bg)
C&L Inventory
метил 2-метилпропеноат (bg)
C&L Inventory
2-Propenoic acid, 2-methyl-, methyl ester
Other
2-Methyl-2- propenoic acid, methyl ester
Registration dossier
2-Methyl-2-propenoic acid methyl
C&L Inventory
2-Methyl-2-propenoic acid methyl ester
C&L Inventory
2-Methyl-2-propenoic acid, methyl ester
C&L Inventory
2-Methyl-propenoic acid, methyl ester
C&L Inventory
2-methylprop-2-enoate
C&L Inventory
2-Propenoic acid, 2-methyl-, methyl ester
C&L Inventory
ECEM bv
Registration dossier
Metahylmethacrylate
Registration dossier
methacrylic acid methylester
C&L Inventory
methly methacrylate
C&L Inventory
Methy methacrylate
Registration dossier
Methyl 2 methylprop-2-enoate
C&L Inventory
Methyl 2-methylprop-2-enoate
C&L Inventory, Registration dossier, Other
methyl 2-methylpropeno
C&L Inventory
methyl 2-methylpropenoate
C&L Inventory
methyl metacrylate
C&L Inventory
Methyl Methacrylat
C&L Inventory
METHYL METHACRYLATE
C&L Inventory, Registration dossier
Methyl Methacrylate
C&L Inventory, Registration dossier
Methyl Methacrylate (stabilized with 6-tert-Butyl-2,4-xylenol)
C&L Inventory
Methyl methacrylate MMA
Registration dossier
methyl methacrylate; methyl 2-methylprop-2-enoate; methyl 2-methylpropenoate
C&L Inventory
Methyl Methylpropenoate
C&L Inventory
Methyl-2-methylprop- 2-eonate
Registration dossier
Methylmethacrylat
Registration dossier
METHYLMETHACRYLATE
C&L Inventory, Registration dossier
Methylmethacrylate
Registration dossier
MMA
Registration dossier
propane-1,2-diol
Registration dossier
2-(Methoxycarbonyl)-1-propene
Registration dossier
2-Methyl-2-propenoic acid, methyl ester
C&L Inventory, Registration dossier
2-Propenoic acid, 2-methyl-, methyl ester
C&L Inventory, Registration dossier
2-Propenoic acid, 2-methyl-, methyl ester (9CI)
Registration dossier
ACRYESTER M.
Registration dossier
Acrylic acid, 2-methyl-, methyl ester
Registration dossier
MAM
Registration dossier
Metacrilato de metilo (Spanish)
Registration dossier
Metakrylan metylu (Polish)
Registration dossier
methacrylate de methyle
Registration dossier
Methacrylate, methyl
Registration dossier
Methacrylic acid methyl ester (6CI, 8CI)
Registration dossier
Methacrylic acid, methyl ester
C&L Inventory, Registration dossier
Methacrylic acid, methyl ester (7CI)
Registration dossier
Methacrylsaeuremethylester
Registration dossier
Methacrylsäuremethyl ester (German)
Registration dossier
Methyl 2-methyl-2-propenoate
Registration dossier
Methyl 2-methylacrylate
Registration dossier
Methyl 2-methylpropenoate
Registration dossier
Methyl methacrylate
Registration dossier
METHYL METHACRYLATE (MMA)
Registration dossier
Methyl-alpha-methacrylate
Registration dossier
Methylester kyseliny methakrylove (Czech)
Registration dossier
Methylmethacrylaat (Dutch)
Registration dossier
Methylmethacrylat
Registration dossier
Methylpropylene-2-carboxylate
Registration dossier
Metil metacrilato (Italian)
Registration dossier
MMA
Registration dossier
Méthacrylate de méthyl (French)
Registration dossier
Pegalan
Registration dossier
Prop-2-enoate, 2-methyl-, methyl
C&L Inventory, Registration dossier
Tetrafluoroethylene
Registration dossier
This substance is a monomer in an imported polymer, therefore no trade names are available and/or relevant.
Registration dossier
VISIOMER®MMA
Registration dossier
1196968-39-4
CAS number
Other
1196968-39-4
Deleted CAS number
Other
1227277-87-3
CAS number
Other
1227277-87-3
Deleted CAS number
Other
1451188-71-8
CAS number
Other
1451188-71-8
Deleted CAS number
Other
1453489-95-6
CAS number
Other
1453489-95-6
Deleted CAS number
Other
162221-54-7
CAS number
Other
162221-54-7
Deleted CAS number
Other
211862-43-0
CAS number
Other
211862-43-0
Deleted CAS number
Other
220713-32-6
CAS number
Other
220713-32-6
Deleted CAS number
Other
607-035-00-6
Index number
C&L Inventory
80-62-6
CAS number
EC Inventory, C&L Inventory, Substance Evaluation - CoRAP, Registration dossier, REACH pre-registration, Other, Aerosols Directive - Flammable Contents - Labelling Requirements, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, Inland Transport of Dangerous Goods Directive, Annex III - ADN, Inland Transport of Dangerous Goods Directive, Annex I - ADR, Inland Transport of Dangerous Goods Directive, Annex II - RID, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Occupational Exposure Limits - 3rd list - Indicative OELVs, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, FCM and Articles Regulation, Annex I - Authorised Substances, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, FCMs Recycled Plastic & Articles Regulation - Annex I - Authorised Use, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
874217-13-7
CAS number
Other
874217-13-7
Deleted CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 2 studies submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Odour
Pungent (100%) [1]
C Substance type
Other (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 0 summaries submitted
  • 0 summaries processed

No data available

Melting/freezing point

Study results
  • 4 studies submitted
  • 1 study processed
R Melting / freezing point
-48 °C @ 101.3 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-48 °C

Boiling point

Study results
  • 6 studies submitted
  • 1 study processed
R Boiling point
100.36 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 4
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
100.36 °C

Density

Study results
  • 10 studies submitted
  • 1 study processed
R Density
0.944 g/cm³ @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1 2
Weight of evidence
Other 2 4
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Relative density at 20°C
0.94

Vapour pressure

Study results
  • 6 studies submitted
  • 1 study processed
R Vapour pressure
30 - 100 hPa @ 16.67 - 39.4 °C [3]

Type of Study provided
Studies with data
Key study 1
Supporting study 2 2
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
37 hPa @ 20 °C

Partition coefficient

Study results
  • 8 studies submitted
  • 2 studies processed
R Log Pow
1.32 - 1.38 @ 20 °C and pH 7 [2]

Type of Study provided
Studies with data
Key study 2
Supporting study
Weight of evidence
Other 1 5
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
1.38 @ 20 °C

Water solubility

Study results
  • 3 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
15.3 g/L @ 20 °C and pH 7 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
15.3 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 8 studies submitted
  • 2 studies processed
R Flash point
10 °C @ 101.3 - 101.325 kPa [2]

Type of Study provided
Studies with data
Key study 2
Supporting study 1
Weight of evidence
Other 3 1 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
10 °C

Auto flammability

Study results
  • 4 studies submitted
  • 1 study processed
R Autoflammability / self-ignition
435 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 1 1
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
435 °C

Flammability

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 1
Sci. unjustified
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Flammable (100%)

Explosiveness

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1 2
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Oxidising

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 2 studies submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
0.53 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
0.53 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 7 studies submitted
  • 1 study processed
R Dissipation half life (DT50)
20.99 - 24.179 h [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 3 2
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half life in air
20.99 h
Degradation rate constant with OH radicals
1.585 m³ molecule-1 d-1

Hydrolysis

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other 2
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in soil

Study results
  • 0 studies submitted
  • 0 studies processed

No data available

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water - screening tests

Study results
  • 12 studies submitted
  • 3 studies processed
C Interpretation of results
Readily biodegradable (67%), Readily biodegradable but failing the 10-day window (33%) [3]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence 3
Other 5 2 1
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Biodegradation in water
Readily biodegradable (100%)
Type of water
Freshwater (100%)

Biodegradation in water & sediment - simulation tests

Data not provided by the registrant

Biodegradation in soil

Study results
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 2
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Henrys law constant (H)

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Distribution modelling

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence
Other 1
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 940 µg/L (1)
Intermittent releases (freshwater) 940 µg/L (1)
Marine water 94 µg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 10 mg/L (1)
Sediment (freshwater) 10.2 mg/kg sediment dw (1)
Sediment (marine water) 102 µg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 1.48 mg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 6 studies submitted
  • 1 study processed
P/RResults
LC50 (4 days) 79 mg/L [1]
NOEC (4 days) 40 mg/L [1]

Type of Study provided
Studies with data
Key study
Supporting study 2
Weight of evidence 1
Other 3
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
NOEC (35 days) 9.4 mg/L [1]
LOEC (35 days) 18.8 mg/L [1]
LC10 (35 days) 16.9 mg/L [1]
LC50 (35 days) 33.7 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 4 studies submitted
  • 1 study processed
P/RResults
EC50 (48 h) 69 mg/L [1]
NOEC (48 h) 48 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 2
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
NOEC (21 days) 37 mg/L [1]
LOEC (21 days) 68 mg/L [1]
EC50 (21 days) 49 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 6 studies submitted
  • 1 study processed
P/RResults
EC50 (72 h) 110 mg/L [2]
NOEC (72 h) 49 - 110 mg/L [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other 3
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
110 mg/L
EC10 or NOEC for freshwater algae
110 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 4 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other 2
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC10 or NOEC for microorganisms
100 mg/L

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons. 1
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 348.4 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 208 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 416 mg/m³ repeated dose toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 13.67 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 1.5 mg/cm² sensitisation (skin)
Acute /short term: (DNEL) 1.5 mg/cm² sensitisation (skin)
EYE Exposure
No hazard identified
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 74.3 mg/m³ repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 104 mg/m³ repeated dose toxicity
Acute /short term: (DNEL) 208 mg/m³ repeated dose toxicity
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 8.2 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
Local Effects
Long-term: (DNEL) 1.5 mg/cm² sensitisation (skin)
Acute /short term: (DNEL) 1.5 mg/cm² sensitisation (skin)
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 8.2 mg/kg bw/day repeated dose toxicity
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 43 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study 1
Supporting study 5 2 1
Weight of evidence 4 2 2
Other 26
Data waiving
no waivers
Study data: dermal absorption
  • 3 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence 2 1
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 16 studies submitted
  • 2 studies processed
P/RResults
LD50 7 900 - 9 400 mg/kg bw (rat) [2]
M/CInterpretations of results
GHS criteria not met [1]

Type of Study provided
oral
Studies with data
Key study
Supporting study 1
Weight of evidence 2
Other 13
Data waiving
no waivers
inhalation
  • 29 studies submitted
  • 1 study processed
P/RResults
LC50 (4 h) 29.8 mg/L air (rat) [1]
M/CInterpretations of results
GHS criteria not met [1]

inhalation
Studies with data
Key study 1
Supporting study 7
Weight of evidence
Other 21
Data waiving
no waivers
dermal
  • 4 studies submitted
  • 1 study processed
P/RResults
LD50 5 000 mg/kg bw (rabbit) [1]
M/CInterpretations of results
GHS criteria not met [1]

dermal
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 3
Data waiving
no waivers
other routes
  • 10 studies submitted
  • 0 studies processed

No automatically processable data submitted

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other 8 2
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed LD50 7 900 mg/kg bw
Inhalation route:
No adverse effect observed LC50 29 800 mg/m³
Dermal route:
No adverse effect observed LD50 5 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 13 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study
Supporting study
Weight of evidence 2
Other 9
Data waiving
Not feasible
Sci. unjustified 2
Exposure cons.
Other
Study data: eye
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study
Supporting study
Weight of evidence 2
Other 4
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (irritating)
Eye
No adverse effect observed (not irritating)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 51 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 8 1
Weight of evidence 4
Other 35 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
Adverse effect observed (sensitising)
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study 1
Weight of evidence
Other 2
Data waiving
no waivers
Study data: inhalation
  • 30 studies submitted
  • 2 studies processed
P/RResults
NOAEC (rat): 104 - 1 640 mg/m³ air [2]
NOAEC (rat): 500 - 1 000 ppm [2]
LOAEC (rat): 416 mg/m³ air [1]
LOAEC (rat): 250 ppm [1]

Study data: inhalation
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other 26
Data waiving
no waivers
Study data: dermal
  • 0 studies submitted
  • 0 studies processed

No data available

Study data: dermal
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
No adverse effect observed NOAEL 124 mg/kg bw/day (chronic, rat)
Inhalation route - systemic effects:
No adverse effect observed NOAEC 2 080 mg/m³ (chronic, rat)
Inhalation route - local effects:
Adverse effect observed NOAEC 104 mg/m³ (chronic, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 25 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 3
Supporting study 3
Weight of evidence 3
Other 16
Data waiving
no waivers
Study data: in vivo
  • 11 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study 2
Weight of evidence 1
Other 6
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVitro
Adverse effect observed (positive)
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 7 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study 2
Supporting study 2
Weight of evidence 1
Other 2
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
No adverse effect observed NOAEL 90.3 mg/kg bw/day (chronic, rat)
Inhalation route:
No adverse effect observed NOAEC 2 050 mg/m³ (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: developmental
  • 10 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study 2
Supporting study 2
Weight of evidence
Other 6
Data waiving
no waivers
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on developmental toxicity
Oral route:
No adverse effect observed NOAEL 450 mg/kg bw/day (subacute, rabbit)
Inhalation route:
No adverse effect observed NOAEC 8 300 mg/m³ (subacute, rat)

Neurotoxicity

Study results
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 4
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant