Registration Dossier

Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: GLP-compliant guideline study, available as unpublished report, no restrictions, fully adequate for assessment.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2003
Report date:
2003

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
Qualifier:
according to guideline
Guideline:
EU Method C.4-C (Determination of the "Ready" Biodegradability - Carbon Dioxide Evolution Test)
Qualifier:
according to guideline
Guideline:
ISO DIS 9439 (Ultimate Aerobic Biodegradability - Method by Analysis of Released Carbon Dioxide)
GLP compliance:
yes (incl. QA statement)
Remarks:
Experimental Toxicology and Ecology, BASF Aktiengesellschaft, 67056 Ludwigshafen/Rhein, Germany

Test material

Constituent 1
Reference substance name:
297132-04-8
EC Number:
608-403-9
Cas Number:
297132-04-8
IUPAC Name:
297132-04-8
Details on test material:
- Name of test substance: 4-(4-Acryloyloxy-butoxycarbonyloxy)-benzoic acid
- Aggregate state/colour: solid / white
- Homogeneity: homogeneous
- Storage conditions: Store at room temperature under light exclusion. Keep dry

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, domestic, non-adapted
Details on inoculum:
- Concentration of sludge in the test assay: 30 mg/L (dry substance).
- Pre-aerated for about two days before the start of the test.
Duration of test (contact time):
28 d
Initial test substance concentrationopen allclose all
Initial conc.:
35 mg/L
Based on:
test mat.
Initial conc.:
20 mg/L
Based on:
other: TOC
Parameter followed for biodegradation estimation
Parameter followed for biodegradation estimation:
CO2 evolution
Details on study design:
- pH: 7.7 before correction, 7.4 after correction
- pH adjusted: no
Reference substance
Reference substance:
aniline

Results and discussion

% Degradation
Parameter:
% degradation (CO2 evolution)
Value:
89
Sampling time:
28 d

BOD5 / COD results

Results with reference substance:
86% within 28 days

Any other information on results incl. tables

Test concentration is equivalent to 20 mg/L TOC. Since the test substance  is poorly soluble in water, no DOC degradation was determined.

Applicant's summary and conclusion

Interpretation of results:
readily biodegradable