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EC number: 690-742-7
CAS number: 1266664-66-7
The test article was evaluated in an exploratory
microbial mutation assay over a concentration range of 100 to 5000µg
/ plate.Salmonella typhimurium test strains
TA1535, TA97a, TA98, and TA100 and Escherichia colitest
strain WP2 uvrA pKM101 were used, with and without metabolic activation
(S-9 liver extract).
The results indicated that the test article, up to the
highest tested concentration, did not produce any 2 -fold or greater
increases in revertants relative to the solvent control in any of the
test strains, either with or without metabolic activation. The positive
control, 2-aminoanthracene (2AA) produced the expected increases in
revertants in all test strains in the presence of metabolic activation. No
precipitate was noted on the plates at any concentration tested. No
precipitate was noted on the plates at any concentration tested.
Inhibition of bacterial lawn growth and revertant growth was noted at
3000 µg / plate and higher in most test strains. In conclusion, the test
article was considered not to be mutagenic in this test system.
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