Registration Dossier
Registration Dossier
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EC number: 229-551-7 | CAS number: 6606-59-3
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Freshwater
- Hazard assessment conclusion:
- PNEC aqua (freshwater)
- PNEC value:
- 4.88 µg/L
- Assessment factor:
- 100
- Extrapolation method:
- assessment factor
- PNEC freshwater (intermittent releases):
- 45 µg/L
Marine water
- Hazard assessment conclusion:
- PNEC aqua (marine water)
- PNEC value:
- 0.488 µg/L
- Assessment factor:
- 1 000
- Extrapolation method:
- assessment factor
STP
- Hazard assessment conclusion:
- PNEC STP
- PNEC value:
- 800 mg/L
- Assessment factor:
- 1
- Extrapolation method:
- assessment factor
Sediment (freshwater)
- Hazard assessment conclusion:
- PNEC sediment (freshwater)
- PNEC value:
- 0.262 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Sediment (marine water)
- Hazard assessment conclusion:
- PNEC sediment (marine water)
- PNEC value:
- 0.026 mg/kg sediment dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for air
Air
- Hazard assessment conclusion:
- no hazard identified
Hazard for terrestrial organisms
Soil
- Hazard assessment conclusion:
- PNEC soil
- PNEC value:
- 0.05 mg/kg soil dw
- Extrapolation method:
- equilibrium partitioning method
Hazard for predators
Secondary poisoning
- Hazard assessment conclusion:
- no potential for bioaccumulation
Additional information
Conclusion on classification
1,6-HDDMA is readily biodegradable but log Pow is > 4,0. Acute toxicity data (based on experimental test or QSAR) are available for all three trophic levels. Chronic data were predicted by QSAR for algae and daphnia. Based on acute toxicity data fish and algae are the most sensitive species within the same range of toxicity. Classification is based on the NOEC algae (72h), QSAR: 0,488 mg/l into category chronic 3, H412. Chronic data fish are available for the more hydrophobic member of the category, TMPTMA, where NOEC fish (32d) was 0.138 mg/l. As 1,6-HDDMA Chronic 3, H412 hydrophobic and the toxicity is based on narcosis a NOEC fish less than 0.1 mg/l is not expected.
Therefore, based on log Pow and NOEC chronic 0,1 - <= 1 mg/l, 1,6-HDDMA will be classified into category chronic 3, H412.
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