Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 207-353-1
CAS number: 464-45-9
A pre-natal developmental toxicity test was performed with isobornyl
acetate according to OECD Guideline 414. 20 female Wistar rats were
exposed by gavage to 0 (control) and 1000 mg/kg bw/day test item between
Days 7 and 16 of gestation, in a limit test. On Day 21 of gestation, the
animals were killed and both dams and fetus were examined. The
investigations showed that the repeated oral exposure to the test item
during the sensitive period of organogenesis, do not cause an impairment
of the general health of dams, not disturbing the intrauterine
development of fetus. The morphological examination of fetuses revealed
no evidence for teratogenic effects of the substance. Therefore, the
NOEL of isobornyl acetate for maternal and fetal developmental toxicity
was determined to be 1000 mg/kg bw/day in rats.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Ce site web utilise des cookies afin de vous garantir la meilleure expérience possible sur nos sites web.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again