α-methyl-1,3-benzodioxole-5-propionaldehyde

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

Not reported

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

comparable to guideline study with acceptable restrictions

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

GLP compliance:

no

Type of method:

gas saturation method

Key result

Temp.:

23 °C

Vapour pressure:

0.092 Pa

Remarks on result:

other: Temperature 22 to 24 °C

Key result

Temp.:

49 °C

Vapour pressure:

1.36 Pa

Key result

Transition / decomposition:

no

Table 1: Results of Measurement of Evaporation Rate and Vapour Concentration

Temperature (°C)	Sample Measurement No.	Carrier gas flow rate (v × 10^6/m³min^-1)	Evaporation rate (k × 10³/mg min^-1)	Vapour concentration ((k/v)/g m^-3)
22 to 24	1	6.77	0.255	0.00376
		56.5	0.264	0.00468
		45.2	0.220	0.00487
		33.9	0.188	0.00556
		0	-	0.00723*
	2	67.7	0.262	0.00386
		56.5	0.240	0.00426
		45.2	0.214	0.00474
		33.9	0.188	0.00554
		0	-	0.0709*
49	1	67.7	3.44	0.0507
		56.5	3.21	0.0569
		45.2	3.03	0.0670
		33.9	2.66	0.0784
		0	-	0.105*
	2	67.7	3.42	0.0505
		56.5	3.18	0.0563
		45.2	2.99	0.0662
		33.9	2.66	0.0786
		0	-	0.105*

*Saturated vapour pressure which was calculated by extrapolation of flow rate 0 to flow rate dependence of vapour concentration.

 

Table 2: Results of Saturated Vapour Concentration and Vapour Pressure Calculation

Temperature (°C)	Sample Measurement No.	Saturated Vapour Concentration (gm^-3)*	Vapour Pressure (Pa)
22 to 24	1	0.00723	0.0932
	2	0.00709	0.0914
	Mean	-	0.0923
49	1	0.105	1.36
	2	0.105	1.36
	Mean	-	1.36

*Saturated vapour pressure which was calculated by extrapolation of flow rate 0 to flow rate dependence of vapour concentration. The value is nominal of saturated vapour concentration after conversion to the volume of gas at 25 °C

Conclusions:

Under the conditions of this study, the vapour pressure of the test material was determined to be 0.0923 Pa at room temperature (22 to 24 ˚C) and 1.36 Pa at 49 ˚C.

Executive summary:

The vapour pressure of the test material was investigated in a study conducted via methodology similar to that outlined in the standardised guideline OECD 104 using the gas saturation method.

In this method vapour pressure is calculated by measuring vapour concentration (amount of evaporation/volume of gas) while carrier gas (mainly nitrogen) flows in contact with the sample of certain temperature generating saturated vapour of the sample. The determination is done based on the assumption that vapour obeys the ideal gas law.

The evaporation rate of sample is obtained by means of measurement of weight decrease rate of sample by electronic balance and carrier gas flow rate is measured by flow meter to obtain vapour concentration of the sample. The determination was carried out at room temperature and 49 °C

Under the conditions of this study, the vapour pressure of the test material was determined to be 0.0923 Pa at room temperature (22 to 24 °C) and 1.36 Pa at 49 °C.

Description of key information

The vapour pressure of the test material was determined to be 0.0923 Pa at room temperature (22 to 24 ˚C) and 1.36 Pa at 49 °C.

Key value for chemical safety assessment

Vapour pressure:

0.092 Pa

at the temperature of:

23 °C

Additional information

The vapour pressure of the test material was investigated in a study conducted via methodology similar to that outlined in the standardised guideline OECD 104 using the gas saturation method. The study was assigned a reliability score of 2 in accordance with the criteria for assessing data quality set forth by Klimisch et al. (1997).

In this method vapour pressure is calculated by measuring vapour concentration (amount of evaporation/volume of gas) while carrier gas (mainly nitrogen) flows in contact with the sample of certain temperature generating saturated vapour of the sample. The determination is done based on the assumption that vapour obeys the ideal gas law.

The evaporation rate of sample is obtained by means of measurement of weight decrease rate of sample by electronic balance and carrier gas flow rate is measured by flow meter to obtain vapour concentration of the sample. The determination was carried out at room temperature and 49 °C

Under the conditions of this study, the vapour pressure of the test material was determined to be 0.0923 Pa at room temperature (22 to 24 °C) and 1.36 Pa at 49 °C.