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EC number: 202-762-1
CAS number: 99-52-5
Primary dermal irritation study was
carried out in 3 New Zealand White rabbits to assess the irritation
potency of test chemical 2-methylbenzene-1,4-diamine(CAS No:-95-70-5)
according to the procedure prescribed in Code of Federal Regulations
(CFR, Title 16, Sec. 1500.42).
2-methylbenzene-1, 4-diamine as
applied as a 2.5% (w/v) preparation to the intact and abraded skin of
each rabbits and skin reactions were noted after 72 hours.
One rabbit had very slight erythema
at the abraded site.
The primary irritation index of
2-methylbenzene-1, 4-diamine (CAS No: - 95-70-5) was 0.3 and no signs
of irritation were observed after 72h.
2-methylbenzene-1, 4-diamine can be
considered not irritating to the skin of New Zealand White rabbits.
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