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EC number: 639-263-7
CAS number: 200575-15-1
This study was performed to assess the skin sensitisation potential of
using the guinea-pig. The method followed was that described in: EEC
Methods for the determination of toxicity, Annex of Directive 92/69/EEC
Method B 6. Skin sensitisaiion. MAGNUSSON, B. and KLIGMAN_A.M. (1970).
Based on the results of a preliminary study and in compliance with the
guideline, the following dose levels were selected:
Intradennal injection 5 w/v in 5% A acetone in Alembieol D
Topical application: 70% w/v in acetone
Challenge application: 70 and 35% w/v in acetone
Ten test and five control guine.a.-pigs were used in this study.
not produce evidence of skin sensitisation (delayed contact
hypersensitivity) in any of the ten test animals.
does not require classification or labelling accordance with GHS
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