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EC number: 203-933-3
CAS number: 112-07-2
reproductive or developmental effects were observed in animals exposed
to 25 ppm or 50 ppm.
In a GLP developmental toxicity study, pregnant rats were exposed to 2
-butoxyethanol vapour at concentrations up to 200ppm during GD6 -15. The
results indicated that exposures from 100ppm upwards caused marked
maternal toxicity, manifest by haemotoxicity and erduced body weight
gain and food consumption. Exposures of 200ppm produced embryotoxicity,
manifest as as increased resorptions and decreased viable implants per
litter) and fetotoxicity (retardations in skeletal ossification). There
was no evidence of teratogenicity. The developmental effects appear to
be secondary to maternal toxicity.
NOAEC (maternal) =50ppm
NOAEC (ebryotoxicity, fetotoxicity) =100ppm
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