Registration Dossier
Registration Dossier
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EC number: 203-933-3 | CAS number: 112-07-2
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Recent, well documented study published in open literature
Data source
Reference
- Reference Type:
- publication
- Title:
- Higher prevalence of breathlessness in elderly exposed to indoor aldehydes and VOCs in a representative sample of French dwellings
- Author:
- Bentayeb M, Billionnet C, Baiz N, Derbez M, Kirchner S, Annesi-Maesano I
- Year:
- 2 013
- Bibliographic source:
- Respiratory Medicine 107, 1598-1607
Materials and methods
- Endpoint addressed:
- other: breathlessness
- Principles of method if other than guideline:
- To determine the respiratory effects of indoor exposures to aldehydes and VOCs, including butoxyethanol, as objectively measured using passive samplers, in elderly living in a population-based representative sample of French dwellings.
- GLP compliance:
- no
Test material
- Reference substance name:
- 2-butoxyethyl acetate
- EC Number:
- 203-933-3
- EC Name:
- 2-butoxyethyl acetate
- Cas Number:
- 112-07-2
- Molecular formula:
- C8H16O3
- IUPAC Name:
- 2-butoxyethyl acetate
Constituent 1
Method
- Ethical approval:
- not applicable
- Exposure assessment:
- measured
- Details on exposure:
- TYPE OF EXPOSURE: Indoor air.
TYPE OF EXPOSURE MEASUREMENT: Area air sampling. VOCs were collected onto Carbograph four adsorbents (Radiello, Fondazione Salvatore Maugeri (FSM)). Adsorbed VOCs were extracted through thermodesorption and analyzed by GC/FID-MS. 567 dwellings were assessed.
Results and discussion
- Results:
- No measurements of 2-butoxyethyl acetate were detected above the LoD (0.3ug/m3).
Applicant's summary and conclusion
- Executive summary:
In a study to measure the levels of indoor air concentrations of a number of volatile organic compounds, 2 -butoxyethyl acetate was not detected.
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