Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 265-182-8
CAS number: 64742-79-6
A complex combination of hydrocarbons obtained from a petroleum stock by treating with hydrogen to convert organic sulfur to hydrogen sulfide which is removed. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C13 through C25 and boiling in the range of approximately 230°C to 400°C (446°F to 752°F).
studies identified in which the skin sensitising potential of other gas
oils was investigated in male Hartley guinea pigs that were dermally
exposed to hydrodesulfurised middle distillate (Klimisch scores = 2, API
the first key study, the test material was administered at a
concentration of 25% v/v in paraffin oil for the induction phase and at
10% v/v in paraffin oil for the challenge application. The
test material induced slight erythema but no oedema following the
challenge application. In
the second study, the test material was administered undiluted for the
induction phase and at a concentration of 10% v/v in paraffin oil for
the challenge application. The
test material elicited well-defined erythema and slight oedema during
the induction phase but no response upon challenge. Based
on the results of these studies, neither sample of hydrodesulfurised
middle distillate was a dermal sensitiser in guinea pigs.
Migrated from Short description of key information:
Two studies identified that investigated skin sensitisation of hydrodesulphurised middle distillate. Data show that other gas oils do not induce or elicit allergic skin reactions in the guinea pig (OECD 406).
Justification for selection of skin sensitisation endpoint:
One of two studies with different samples of hydrodesulphurised middle distillate. Both studies negative. Key study selected as it used a higher induction concentration.
Gas Oils do not meet the criteria for classification as sensitising to
the skin according to EU CLP Regulation (EC No. 1272/2008).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Ce site web utilise des cookies afin de vous garantir la meilleure expérience possible sur nos sites web.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again