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EC number: 231-150-7
CAS number: 7440-41-7
Table 1: Animals with positive reactions after challange
The skin sensitizing potential of beryllium metal powder was
investigated in guinea pigs according to OECD guideline 406. For
induction of sensitization, male Dunkin-Hartley Guinea Pigs were exposed
to the highest technically feasibile concentration of the test item in
polyethylene glycol (PEG 300) by intradermal injection together with
immunostimulant (Freud's Complete Adjuvant). One week later, the animals
were exposed to the test item in PEG 300 by 48 h occlusive epidermal
application. Two weeks later, reactions were challanged by epidermal
application of test item in PEG 300 (same procedure as for epidermal
induction, but different site).
None of the animals showed signs of contact hypersensitivity.
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