Registration Dossier
Registration Dossier
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EC number: 231-150-7 | CAS number: 7440-41-7
Endpoint summary
Administrative data
Description of key information
- An up to date acute oral toxicity study is available that reports no toxicity at the maximum dose of 2000 mg/kg bw.
- No studies on dermal toxicity are available.
- A set of non-standard studies with single inhalation exposure are available, but not suitable for setting a LC50.
- Only airborne exposures to soluble beryllium compounds are associated with acute beryllium disease. Exposure to beryllium metal has not been found to be associated with acute or short-term respiratory reactions.
Eisenbud M. The Standard for Control of Chronic Beryllium Disease. Appl Occup Environ Hyg 13(1): 25–31 (1998).
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- mg/kg bw
Additional information
Justification for classification or non-classification
- oral toxicity: Be metal is non-toxic via the oral route and does not need to be classified for acute oral toxicity according to CLP
(REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL) as implementation
of UN-GHS in the EU.
- dermal toxicity: The dermal toxicity Be metal cannot be assessed as no reliable study is available. Given the absence of oral toxicity a classification for acute dermal toxicity is deemed unjustified according to CLP (REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL) as implementation of UN-GHS in the EU.
- inhalation toxicity: Beryllium metal is non-toxic via the inhalation route and does not need to be classified for acute oral toxicity according to CLP (REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL)
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