Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
respiratory sensitisation
Remarks:
other: DEREK Nexus software
Type of information:
other: DEREK Nexus
Adequacy of study:
weight of evidence
Study period:
2012
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: not OECD method was used

Data source

Reference
Reference Type:
other: DEREK Nexus software
Title:
Unnamed
Year:
2012
Report date:
2012

Materials and methods

Test guideline
Qualifier:
no guideline followed
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
(1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl(2S)-2-methylbutanoate
EC Number:
700-442-0
Cas Number:
73573-88-3
Molecular formula:
C23H34O5
IUPAC Name:
(1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl(2S)-2-methylbutanoate

Results and discussion

Applicant's summary and conclusion

Interpretation of results:
not sensitising
Conclusions:
Computational toxicology summary was prepared by DEREK Nexus version 2.0.2 software, and the result for respiratory sensitisation is negative.
Executive summary:

Computational toxicology summary was prepared by DEREK Nexus version 2.0.2 software, and the result for respiratory sensitisation is negative.