Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Biodegradability in water

Ready biodegradability:


One study (Tecnologia America Latina, 2002), scored as reliability 2 according to Klimisch and selected as a key study, was performed according to ISO14593 (similar to OECD guideline 310). In this study, the biodegradation of 4-tert-butylpyrocatechol (4 -TBC) was followed during 28 days, at an initial concentration of 20 mg carbon/L (27.7 mg 4-TBC/L). Inoculum used in the test was an activated sludge at a concentration of 4 mg/L taking in an aeration basin of a sewage treatment plant of domestic effluents. After 28 days, the percentage of degradation was 24.7%based on CO2evolution. On the basis of this study, 4-tert-butylpyrocatechol is not readily biodegradable.

Inherent biodegradability:


One study in aerobic conditions (Harlan, 2010), scored as reliability 1 according to Klimisch, was selected as a key study. The inherent biodegradability of 4 -tert-butylpyrocatechol (4 -TBC) (initial concentration: 143 mg/L), was tested in a Zahn-Wellens test during 28 days according to OECD guideline 302B. Inoculum used in a study was 300 mg/L of a sludge from a wastewater treatment plant, adapted.

After 28 days, the corresponding percentage of biodegradation obtained was 91% of DOC removal. More that 70% degradation of 4 -TBC occurred within the first seven days of the test, including the lag-phase and the log-phase. The log-phase was lower than 3 days. Under the test conditions, 4 -TBC is considered as inherent ultimately biodegradable.

Additional information