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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Reference
Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2003
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Qualifier:
according to guideline
Guideline:
OECD Guideline 305 C (Bioaccumulation: Test for the Degree of Bioconcentration in Fish)
GLP compliance:
not specified
Test organisms (species):
other: carp (fish)
Test type:
flow-through
Water / sediment media type:
natural water: freshwater
Total exposure / uptake duration:
42 d
pH:
7
Dissolved oxygen:
ca. 7ppm
Key result
Type:
BCF
Value:
>= 0.5 - <= 7 L/kg
Conclusions:
BCF = 0.5 -7

Description of key information

Key value for chemical safety assessment

BCF (aquatic species):
7 dimensionless

Additional information

Data from an OECD 305C guideline study on bioaccumulation, conducted in carp at 0.4 and 0.04 mg substance/L, demonstrated limited or no potential for1,2-dichloropropaneto bioaccumulate (BCF = 0.5-7; MITI, 1992). The published data present only limited methodological details. This low/no potential for bioaccumulation is supported by a calculated BCF of 1.29 (Howard, 1990; McKayet al., 1993).