Registration Dossier
Registration Dossier
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EC number: 213-313-4 | CAS number: 936-49-2
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Title:
- No information
- Author:
- Anonymous
- Year:
- 2 007
- Bibliographic source:
- IUCLID4 data set, 2007
Materials and methods
Test guideline
- Guideline:
- other: in accordance with the recommended guidelines of the USA Interagency Regulatory Liaison Group
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2-phenyl-2-imidazoline
- EC Number:
- 213-313-4
- EC Name:
- 2-phenyl-2-imidazoline
- Cas Number:
- 936-49-2
- Molecular formula:
- C9H10N2
- IUPAC Name:
- 2-phenyl-4,5-dihydro-1H-imidazole
Constituent 1
Test animals / tissue source
- Species:
- rabbit
Test system
- Vehicle:
- unchanged (no vehicle)
- Amount / concentration applied:
- 0.1 ml of 100% substance
- Number of animals or in vitro replicates:
- 6
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- mean
- Time point:
- other: 24h
- Score:
- 4
- Max. score:
- 6
- Reversibility:
- not specified
- Remarks on result:
- other: highly irritating
Applicant's summary and conclusion
- Interpretation of results:
- highly irritating
- Remarks:
- Migrated information Xi;R41 Criteria used for interpretation of results: EU
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