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EC number: 911-174-0
CAS number: -
Doses up to and including 16 µg per plate did not cause any
bacteriotoxic effects : Total bacteria counts remained unchanged and no
inhibition of growth was observed. At higher doses, the substance had a
strong, strain-specific bacteriotaxic effect, so that this range could
only be used to a limited extent up to and including 32 µg per plate for
Vorprodukt Katalysator WAZ 5596B was screened with one plate per dose
using the Salmonellajmicrosome test (plate incorporation
and preincubation method) for point mutagenic effects in doses of up to
and including 128 µg per plate on five Salmonella
typhimurium LT2 mutants. These comprised the histidine-auxotrophic
strains TA 1535, TA 100, TA 1537, TA 98 and TA 102.
Evidence of mutagenic activity of Vorprodukt Katalysator WAZ 5596B was
not seen. No biologically relevant increase in the mutant count, in
comparison with the negative controls, was observed .
The positive controls sodium azide, nitrofurantoin, 4-nitro-1,2-phenylene
diamine, cumene hydroperoxide and 2-aminoanthracene
had a marked mutagenic effect, as was seen by a biologically relevant
increase in mutant colonies compared to the corresponding negative
Therefore, Vorprodukt Katalysator WAZ 55968 was considered to be
non-mutagenic without and with 89 mix in the plate incorporation as well
as in the preincubation modification of the Salmonella/microsome test.
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