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EC number: 911-174-0
CAS number: -
A single dose of 3100 and 5000 mg/kg bw Vorprodukt Katalysator WAZ 5596
B caused to following signs of intoxication: sedation, cyanosis,
disordered breathing and a reduction of general condition rough fur, and
bloody eye lids. An increased diuresis was observed on male rats and
female rats dosed with 3100 or 2000 mg/kg bw, respectively. Staggered
gait and bloody snouts were obvious on males with 3100 and 5000 mg/kg bw
and on females with 2000 to 5000 mg/kg bw. Sedation and prone position
was seen at one male and several female rats at doses of 5000 mg/kg bw
or 3100 and 5000 mg/kg bw, respectively.
Gasping had three female rats. One male and one female each dosed with
5000 mg/kg bw had signs of paralysis on the hind legs. Weight reduction
was observed on 3 females dosed with 2000 mg/kg bw and 1 male rats dosed
with 3100 mg/kg bw during the first observation week.
Additional, with doses of 200 to 400 µl/kg bw a weight reduction was
Symptoms were evident 1 hour after application and continued until the
last day of the examination period. Deads occured after 3 hours until
Three groups of 5 male and 5 female Wister rats (avarage weight 173-177
g) each reveived per gavage 2000, 3100 or 5000 mg/kg bw Vorprodukt
Katalysator WAZ 5596 B. The animals were observed for mortality, weight
and clinical signs through day 14. A gross pathological examination was
performed on animals which died during the observation period or were
killed after termination of the study. The approximative LD50 was 3100
to 5000 mg/kg bw for male rats and 2500 mg/kg bw for female rats.
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