Registration Dossier
Registration Dossier
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EC number: 229-713-7 | CAS number: 6674-22-2
PBT assessment
Administrative data
PBT assessment: overall result
- Name:
- 1,8-diazabicyclo[5.4.0]undec-7-ene
- Type of composition:
- legal entity composition of the substance
- State / form:
- liquid
- Reference substance:
- 1,8-diazabicyclo[5.4.0]undec-7-ene
- Name:
- 1,8-diazabicyclo[5.4.0]undec-7-ene
- Type of composition:
- boundary composition of the substance
- State / form:
- liquid
- Reference substance:
- 1,8-diazabicyclo[5.4.0]undec-7-ene
- PBT status:
- the substance is not PBT / vPvB
- Justification:
An evaluation of the inherent properties of 1,8-Diazabicyclo-5-4-0-undecene-7 (CAS# 6674-22-2) is performed against Annex XIII criteria. If insufficient data were available, the screening criteria as laid down in ECHA Guidance on information requirements and chemical safety assessment R.11: PBT Assessment were applied.
The available evidence on degradation is not sufficient for an assessment based on the Annex XIII criteria for persistence (P and vP). As the substance is concluded to be neither readily nor inherently biodegradable, it should be considered potentially P/vP from a precautionary point of view until further data become available.
In an experimental OECD 305 guideline study the BCF was determined to be 3.6 at a test concentration level of 0.05 mg/L.
In addition, this substance has a low log Kow (measured log Kow at pH 7.0 and 25 °C: <-2.2; BASF SE, 2011), indicating a low potential for bioaccumulation.
Regarding "T", chronic data are available for algae and daphnids, with daphnids being the most sensitive organism in acute toxicity studies. The 21-d NOEC was determined to be >=12 mg/L and hence is above the critical value of 0.01 mg/L for chronic aquatic studies. The substance holds no relevant classification. Therefore the substance is assessed to be not toxic (not T).
It can be concluded that the substance is neither a PBT nor a vPvB substance.
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