Registration Dossier
Registration Dossier
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EC number: 812-024-6 | CAS number: 1638534-24-3
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 000
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- GLP compliance:
- yes
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- (3R)-N-[(1S)-phenylethyl]-2,3,4,9-tetrahydro-1H-carbazol-3-amine hydrochloride
- EC Number:
- 812-024-6
- Cas Number:
- 1638534-24-3
- Molecular formula:
- C20H23ClN2
- IUPAC Name:
- (3R)-N-[(1S)-phenylethyl]-2,3,4,9-tetrahydro-1H-carbazol-3-amine hydrochloride
Constituent 1
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 3.5
- Temp.:
- 40 °C
- pH:
- 9.9
- Remarks on result:
- other: Reference log Pow- values in the OECD guideline presumably refer ro 25 °C. The column temperature was 40 °C. However, the influence of this temperature difference on the calculated log P value lies within the range of the error of the method.
Applicant's summary and conclusion
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Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
