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Physical & Chemical properties

Water solubility

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Administrative data

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
August 1998
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
1995
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
1992
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Key result
Water solubility:
> 100 g/L
Conc. based on:
test mat.
Loading of aqueous phase:
500 g/L
Incubation duration:
> 1 - < 72 h
Temp.:
20 °C
pH:
> 1 - < 3
Remarks on result:
other: the test article is not stable under the conditions of the test
Details on results:
To determine the solubility of GAP in water more precisely, a simplified test with shorten equilibration times (1, 3 and 6 hours) at room temperature was performed. Each test was performed in duplicate. In conclusion, the water solubility of GAP at room temperature was estimated to be at least 100 g/l, but the test article is not stable under the conditions of the test. Although the test article was completely dissolved after 72 hours (1600 g/l added), only about 700 g/l were found by titration. The water solubility was not corrected for the purity of the test article neither.
Conclusions:
The water solubility of the test item was determined according to OECD 105 to be > 100 g/L.
Executive summary:

The water solubility of the test item was determined in accordance with OECD TG 105 at a temperature of 20.0 °C. In conclusion, the water solubility of GAP at room temperature was estimated to be at least 100 g/L, but the test article is not stable under the conditions of the test.

Description of key information

The water solubility of the test item was determined according to OECD 105 to be > 100 g/L.

Key value for chemical safety assessment

Additional information

The water solubility of the test item was determined in accordance with OECD TG 105 at a temperature of 20.0 °C. In conclusion, the water solubility of GAP at room temperature was estimated to be at least 100 g/L, but the test article is not stable under the conditions of the test.