Diarsenic trioxide

Guidance on Safe Use

First-aid measures

SYMPTOMS

Inhalation:

May give off gas, vapor or dust that is very irritating or corrosive to the respiratory system.

Ingestion:

Very toxic if swallowed. May cause burns to mouth, throat and stomach.

Skin contact:

Corrosive to the skin. Causes burns.

Eye contact:

Corrosive to eyes. Causes burns.

FIRST AID MEASURES

Inhalation:

If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention immediately.

Ingestion:

Do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical attention immediately.

Skin contact:

In case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Clean shoes thoroughly before reuse. Get medical attention immediately.

Eye contact:

In case of contact, immediately flush eyes with plenty of water for at least 15 minutes.

Get medical attention immediately.

Fire-fighting measures

EXTINGUISHING MEDIA

Suitable:

Use an extinguishing agent suitable for the surrounding fire.

Not suitable:

None known.

Special exposure hazards:

No specific fire or explosion hazard. Promptly isolate the scene by removing all persons from the Vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training. This material is very toxic to aquatic organisms. Fire water contaminated with this material must be contained and prevented from being discharged to any waterway, sewer or drain.

Hazardous combustion products:

Decomposition products may include the following materials: metal OXide/oxides

Special protective equipment for firefighters:

Fire-fighters should wear appropriate protective equipment and self-contained breathing apparatus (SCBA) with a full face-piece operated in positive pressure mode.

Accidental release measures

Personal precautions:

No action shall be taken involVing any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see section Exposure controls / personal protection).

Environmental precautions:

Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). Water polluting material. May be harmful to the environment if released in large quantities.

Methods for cleaning up:

Move containers from spill area. Approach release from upwind. Prevent entry into sewers, water courses, basements or confined areas. Vacuum or sweep up material and place in a designated, labeled waste container. Dispose of via a licensed waste disposal contractor.

Handling and storage

Handling:

Do not ingest. Do not get in eyes, on skin or on clothing. Keep container closed. Use only with adequate ventilation. Do not breathe dust. Avoid contact of spilled material and runoff with soil and surface waterways. Avoid exposure. Use suitable protective equipment ( see section Exposure controls / personal protection). Avoid generation of dust.

Storage:

Keep container tightly closed. Keep container in a well-ventilated area. Keep away from incompatibles as acids and Hydrogen source.

Additional information:

Evolves arsine (toxic and flammable gas) on contact with brass, steel and other metals.

Packaging materials Recommended:

Use original container.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

UN1561

Shipping

Labels:

6

Special provisions / remarks

Special provisions:

Hazard Identification Number: 60
Limited quantity: LQ18
CEFIC Tremcard: 61GT5-11

Inland waterway transport (UN RTDG/ADN(R))

UN number:

UN1561

Shipping information

Proper shipping name and description:

ARSENIC TRIOXIDE

Labels:

6

Remarks

Marine transport (UN RTDG/IMDG)

UN number:

UN1561

Shipping information

Proper shipping name and description:

ARSENIC TRIOXIDE

Labels:

6

Remarks

Air transport (UN RTDG/ICAO/IATA)

UN number:

UN1561

Shipping information

Proper shipping name and description:

ARSENIC TRIOXIDE

Labels:

6

Special provisions / remarks

Remarks:

Passenger and Cargo Aircraft - Quantity limitation: 2S kg
Cargo Aircraft Only - Quantity limitation: 100 kg
Limited Quantities- Passenger Aircraft: Quantity limitation: 1 kg

SpecialProvisions

Exposure controls / personal protection

EXPOSURE CONTROLS

Occupational exposure controls:

If user operations generate dust, fumes, gas, vapor or mist, use process enclosures, local exhaust ventilation or other engineering controls to keep worker exposure to airborne contaminants below any recommended or statutory limits.

Respiratory protection:

Use a properly fitted, air-purifying or air-fed respirator complying with an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator. Recommended: EU : disposable particulate mask or half-face mask type P3 (EN 140-143 or EN 149) . USA and Canada: Wear NIOSH approved, properly fitted HEPA type respirator.

Skin protection / Hand protection:

chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary. Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product.

Recommended: Wear suitable gloves. EU : (EN 374)

Eye protection:

Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liqUid splashes, mists, gases or dusts. Recommended: EU: safety glasses with side-shields (EN 166) . USA: Wear ANSI compliant safety glasses with side shields. Canada: Wear CSA approved safety glasses with side shields. Mono goggles provide better protection in dusty conditions.

Environmental exposure controls:

Emissions from ventilation or work process equipment should be checked to ensure they comply with the requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels.

HYGIENE MEASURES

General information:

Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed.

Stability and reactivity

Stability:

The product is stable. Under normal conditions of storage and use, hazardous polymerization will not occur.

Materials to avoid:

Reactive or incompatible with the following materials: reducing materials. Evolves arsine (toxic and flammable gas) on contact with brass, steel and other metals.

Hazardous decomposition products:

Under normal conditions of storage and use, hazardous decomposition products should not be  produced.

Disposal considerations

Methods of disposal:

The generation of waste should be avoided or minimized wherever possible. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. This product is recyclable. Consideration of disposal via this route should be given.

European waste catalogue (EWC):

Not available.

Hazardous waste:

The classification of the product may meet the criteria for a hazardous waste.