carcinogens-mutagens-dir-2004-37

Carc and Muta Directive, Annex I - Substances, Mixtures & Processes

EU. Substances, Mixtures, Related Processes: Annex I & Art. 2, Dir 2004/37/EC (CMRD), as amended by Dir (EU) 2022/431, 16 March 2022

This list contains a non-exhaustive inventory of substances based on Art. 2 carcinogen, mutagen and reprotoxin (CMR) definitions and Annex I of the Carcinogens, Mutagens and Reprotoxins Directive (CMRD). Category 1A and 1B CMRs are derived from the CLP Regulation's Table 3 of Annex VI (1272/2008/EC). Employers are obligated to minimize worker exposure to these agents as far as possible, and must arrange for medical surveillance of workers exposed to these substances.

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Last updated 18 avril 2024. Database contains 1292 unique substances/entries.
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Substance Name
EC No.
CAS No.
 
Naphtha (petroleum), full-range coker; Low boiling point naphtha — unspecified [A complex combination of hydrocarbons produced by the distillation of products from a fluid coker. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C4 through C15 and boiling in the range of approximately 43o C to 250o C (110°F-500°F).]
A complex combination of hydrocarbons produced by the distillation of products from a fluid coker. It consists predominantly of unsaturated hydrocarbons having carbon numbers predominantly in the range of C4 through C15 and boiling in the range of approximately 43°C to 250°C(110°F-500°F).
270-991-4
68513-02-0
 Details
Naphtha (petroleum), full-range alkylate; Low boiling point modified naphtha [A complex combination of hydrocarbons produced by distillation of the reaction products of isobutane with monoolefinic hydrocarbons usually ranging in carbon numbers from C3 through C5 It consists of predominantly branched chain saturated hydrocarbons having carbon numbers predominantly in the range of C7 through C12 and boiling in the range of approximately 90 °C to 220 °C (194°F to 428°F).]
A complex combination of hydrocarbons produced by distillation of the reaction products of isobutane with monoolefinic hydrocarbons usually ranging in carbon numbers from C3 through C5. It consists of predominantly branched chain saturated hydrocarbons having carbon numbers predominantly in the range of C7 through C12 and boiling in the range of approximately 90°C to 220°C (194°F to 428°F).
265-066-7
64741-64-6
 Details
Naphtha (petroleum), full-range alkylate, butane-contg.; Low boiling point modified naphta [A complex combination of hydrocarbons produced by the distillation of the reaction products of isobutane with monoolefinic hydrocarbons usually ranging in carbon numbers from C3 through C5. It consists of predominantly branched chain saturated hydrocarbons having carbon numbers predominantly in the range of C7 through C12 with some butanes and boiling in the range of approximately 35 °C to 200 °C (95 °F to 428 °F).]
A complex combination of hydrocarbons produced by the distillation of the reaction products of isobutane with monoolefinic hydrocarbons usually ranging in carbon numbers from C3 through C5. It consists of predominantly branched chain saturated hydrocarbons having carbon numbers predominantly in the range of C7 through C12 with some butanes and boiling in the range of approximately 35°C to 200°C (95°F to 428°F).
271-267-0
68527-27-5
 Details
Naphtha (petroleum), clay-treated light straight-run; Low boiling point naphtha — unspecified [A complex combination of hydrocarbons resulting from treatment of light straight-run naphtha with a natural or modified clay, usually in a percolation process to remove the trace amounts of polar compounds and impurities present. It consists of hydrocarbons having carbon numbers predominantly in the range of C7 through C10 and boiling in the range of approximately 93 °C to 180 °C (200°F to 356°F).]
A complex combination of hydrocarbons resulting from treatment of light straight-run naphtha with a natural or modified clay, usually in a percolation process to remove the trace amounts of polar compounds and impurities present. It consists of hydrocarbons having carbon numbers predominantly in the range of C7 through C10 and boiling in the range of approximately 93°C to 180°C (200°F to 356°F).
271-263-9
68527-22-0
 Details
Naphtha (petroleum), clay-treated full-range straight-run; Low boiling point naphtha -unspecified [A complex combination of hydrocarbons resulting from treatment of full-range straight- run naphtha with natural or modified clay, usually in a percolation process to remove the trace amounts of polar compounds and impurities present. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately - 20o C to 220o C (- 4°F to 429°F).]
A complex combination of hydrocarbons resulting from treatment of full-range straight-run naphtha with natural or modified clay, usually in a percolation process to remove the trace amounts of polar compounds and impurities present. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately -20°C to 220°C (-4°F to 429°F).
271-262-3
68527-21-9
 Details
Naphtha (petroleum), chemically neutralized light; Low boilingpoint naphtha -unspecified [A complex combination of hydrocarbons produced by a treating process to remove acidic materials. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately - 20 °C to 190°C (-4 °F to 374 °F).]
A complex combination of hydrocarbons produced by a treating process to remove acidic materials. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately minus 20°C to 190°C (-4°F to 374°F).
265-123-6
64742-23-0
 Details
Naphtha (petroleum), chemically neutralized heavy; Low boilingpoint naphtha — unspecified [A complex combination of hydrocarbons produced by a treating process to remove acidic materials. It consists of hydrocarbons having carbon numbers predominantly in the range of C6 through C12 and boiling in the range of approximately 65o C to 230o C (149°F to 446°F).]
A complex combination of hydrocarbons produced by a treating process to remove acidic materials. It consists of hydrocarbons having carbon numbers predominantly in the range of C6 through C12 and boiling in the range of approximately 65°C to 230°C (149°F to 446°F).
265-122-0
64742-22-9
 Details
Naphtha (petroleum), catalytic reformed; Low boiling point cat-reformed naphtha [A complex combination of hydrocarbons produced by the distillation of products from a catalytic reforming process. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C12 and boiling in the range of approximately 30 °C to 220 °C (90°F to 430°F). It contains a relatively large proportion of aromatic and branched chain hydrocarbons. This stream may contain 10 vol. % or more benzene.]
A complex combination of hydrocarbons produced by the distillation of products from a catalytic reforming process. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C12 and boiling in the range of approximately 30°C to 220°C (90°F to 430°F). It contains a relatively large proportion of aromatic and branched chain hydrocarbons. This stream may contain 10 vol. % or more benzene.
273-271-8
68955-35-1
 Details
Naphtha (petroleum), catalytic reformed light, arom.-free fraction; Low boiling point naphtha -unspecified [A complex combination of hydrocarbons remaining after removal of aromatic compounds from catalytic reformed light naphtha in a selective absorption process. It consists predominantly of paraffinic and cyclic compounds having carbon numbers predominantly in the range of C5 to C8 and boiling in the range of approximately 66o C to 121o C (151°F to250°F).]
A complex combination of hydrocarbons remaining after removal of aromatic compounds from catalytic reformed light naphtha in a selective absorption process. It consists predominantly of paraffinic and cyclic compounds having carbon numbers predominantly in the range of C5 to C8 and boiling in the range of approximately 66°C to 121°C (151°F to 250°F).
285-510-3
85116-59-2
 Details
Naphtha (petroleum), catalytic dewaxed; Low boiling point naphtha -unspecified [A complex combination of hydrocarbons obtained from the catalytic dewaxing of a petroleum fraction. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C12 and boiling in the range of approximately 35°C to 230 °C (95°F to 446°F).]
A complex combination of hydrocarbons obtained from the catalytic dewaxing of a petroleum fraction. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C5 through C12 and boiling in the range of approximately 35°C to 230°C (95°F to 446°F).
265-170-2
64742-66-1
 Details
Naphtha (petroleum), catalytic cracked light distd.; Low boiling point cat-cracked naphtha [A complex combination of hydrocarbons produced by the distillation of products from a catalytic cracking process. It consists of hydrocarbons having carbon numbers predominantly in the range of C1 through C5.]
A complex combination of hydrocarbons produced by the distillation of products from a catalytic cracking process. It consists of hydrocarbons having carbon numbers predominantly in the range of C1 through C5.
272-185-8
68783-09-5
 Details
Naphtha (petroleum), arom.-contg.; Low boilingpoint naphtha — unspecified
271-635-0
68603-08-7
 Details
Naphtha (petroleum) sweetened; Low boiling point naphtha -unspecified [A complex combination of hydrocarbons obtained by subjecting a petroleum naphtha to a sweetening process to convert mercaptans or to remove acidic impurities. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C12 and boiling in the range of approximately - 10o C to 230o C (14°F to 446°F).]
A complex combination of hydrocarbons obtained by subjecting a petroleum naphtha to a sweetening process to convert mercaptans or to remove acidic impurities. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C12 and boiling in the range of approximately minus 10°C to 230°C (14°F to 446°F).
265-089-2
64741-87-3
 Details
Naphtha (coal), solvent extn., hydrocracked [Fraction of the distillate obtained by hydrocracking of coal extract or solution produced by the liquid solvent extraction or supercritical gas extraction processes and boiling in the range of approximately 30 °C to 180 °C (86°F to 356°F). Composed primarily of aromatic, hydrogenated aromatic and naphthenic compounds, their alkyl derivatives and alkanes with carbon numbers predominantly in the range of C4 to C9. Nitrogen, sulfur and oxygen-containing aromatic and hydrogenated aromatic compounds are also present.]
Fraction of the distillate obtained by hydrocracking of coal extract or solution produced by the liquid solvent extraction or supercritical gas extraction processes and boiling in the range of approximately 30°C to 180°C (86°F to 356°F). Composed primarily of aromatic, hydrogenated aromatic and naphthenic compounds, their alkyl derivatives and alkanes with carbon numbers predominantly in the range of C4 to C9. Nitrogen, sulfur and oxygen-containing aromatic and hydrogenated aromatic compounds are also present.
302-690-1
94114-54-2
 Details
Naphtha (coal), distn. residues; Light Oil Redistillate, high boiling [The residue remaining from the distillation of recovered naphtha. Composed primarily of naphthalene and condensation products of indene and styrene.]
The residue remaining from the distillation of recovered naphtha. Composed primarily of naphthalene and condensation products of indene and styrene.
292-636-2
90641-12-6
 Details
N-methylformamide
204-624-6
123-39-7
 Details
N-methylacetamide
201-182-6
79-16-3
 Details
N-methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone
212-828-1
872-50-4
 Details
N-ethyl-2-pyrrolidone; 1-ethylpyrrolidin-2-one
220-250-6
2687-91-4
 Details
N-carboxymethyliminobis(ethylenenitrilo)tetra (acetic acid)
200-652-8
67-43-6
 Details
N-[6,9-dihydro-9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-6-oxo-1H-purin-2-yl]acetamide
424-550-1
84245-12-5
 Details
N-(hydroxymethyl)acrylamide; methylolacrylamide; [NMA]
213-103-2
924-42-5
 Details
N-(2-nitrophenyl)phosphoric triamide
477-690-9
874819-71-3
 Details
N,N-dimethylhydrazine
200-316-0
57-14-7
 Details
N,N-dimethylacetamide
204-826-4
127-19-5
 Details
N,N-dimethyl-p-toluidine
202-805-4
99-97-8
 Details
N,N,N',N'-tetramethyl-4,4'-methylendianiline
202-959-2
101-61-1
 Details
N,N'-methylenedimorpholine; N,N'-methylenebismorpholine [formaldehyde released from N,N'-methylenebismorpholine]; [MBM]
227-062-3
5625-90-1
 Details
N,N'-diacetylbenzidine
210-338-2
613-35-4
 Details
N, N-dimethylformamide; dimethyl formamide
200-679-5
68-12-2
 Details
N, N-(dimethylamino)thioacetamide hydrochloride
435-470-1
27366-72-9
 Details
molybdenum nickel tetraoxide
238-034-5
14177-55-0
 Details
molybdenum nickel oxide
-
12673-58-4
 Details
molybdenum nickel hydroxide oxide phosphate
268-585-7
68130-36-9
 Details
millerite
-
1314-04-1
 Details
methylmercuric chloride
204-064-2
115-09-3
 Details
methylhydrazine
200-471-4
60-34-4
 Details
methyl-phenylene diamine
246-910-3
25376-45-8
 Details
methyl-ONN-azoxymethyl acetate; methyl azoxy methyl acetate
209-765-7
592-62-1
 Details
methyl acrylamidomethoxyacetate (containing ≥ 0,1 % acrylamid)
MAGME 100 MONOMEER
401-890-7
77402-03-0
 Details
methyl acrylamidoglycolate (containing ≥ 0,1 % acrylamide)
MAGME(R) 200 MONOMER
403-230-3
77402-05-2
 Details
methoxyacetic acid
210-894-6
625-45-6
 Details
mercury
231-106-7
7439-97-6
 Details
Manufacture of auramine
-
-
 Details
mancozeb (ISO); manganese ethylenebis(dithiocarbamate) (polymeric) complex with zinc salt
616-995-5
8018-01-7
 Details
m-bis(2,3-epoxypropoxy)benzene; resorcinol diglycidyl ether
202-987-5
101-90-6
 Details
Lubricating oils; Baseoil — unspecified [A complex combination of hydrocarbons obtained from solvent extraction and dewaxing processes. It consists predominantly of saturated hydrocarbons having carbon numbers in the range C15 through C50.]
A complex combination of hydrocarbons obtained from solvent extraction and dewaxing processes. It consists predominantly of saturated hydrocarbons having carbon numbers in the range C15 through C50.
278-012-2
74869-22-0
 Details
Lubricating oils (petroleum), hydrocracked nonarom. solvent-deparaffined; Baseoil — unspecified
295-424-8
92045-43-7
 Details
Lubricating oils (petroleum), C>25, solvent-extd., deasphalted, dewaxed, hydrogenated; Baseoil — unspecified [A complex combination of hydrocarbons obtained by solvent extraction and hydrogenation of vacuum distillation residues. It consists predominantly of hydrocarbons having carbon numbers predominantly greater than C25 and produces a finished oil with a viscosity in the order of 32cSt to 37cSt at 100 °C (212 °F).]
A complex combination of hydrocarbons obtained by solvent extraction and hydrogenation of vacuum distillation residues. It consists predominantly of hydrocarbons having carbon numbers predominantly greater than C25 and produces a finished oil with a viscosity in the order of 32cSt to 37cSt at 100°C (212°F).
309-874-0
101316-69-2
 Details
Lubricating oils (petroleum), C24-50, solvent-extd., dewaxed, hydrogenated; Baseoil — unspecified [A complex combination of hydrocarbons obtained by solvent extraction and hydrogenation of atmospheric distillation residues. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C24 through C50 and produces a finished oil with a viscosity in the order of 16cSt to 75cSt at 40 °C (104 °F).]
A complex combination of hydrocarbons obtained by solvent extraction and hydrogenation of atmospheric distillation residues. It consists predominantly of hydrocarbons having carbon numbers predominantly in the range of C24 through C50 and produces a finished oil with a viscosity in the order of 16cSt to 75cSt at 40°C (104°F).
309-877-7
101316-72-7
 Details
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