carcinogens-mutagens-dir-2004-37

Carc and Muta Directive, Annex I - Substances, Mixtures & Processes

EU. Substances, Mixtures, Related Processes: Annex I & Art. 2, Dir 2004/37/EC (CMRD), as amended by Dir (EU) 2022/431, 16 March 2022

This list contains a non-exhaustive inventory of substances based on Art. 2 carcinogen, mutagen and reprotoxin (CMR) definitions and Annex I of the Carcinogens, Mutagens and Reprotoxins Directive (CMRD). Category 1A and 1B CMRs are derived from the CLP Regulation's Table 3 of Annex VI (1272/2008/EC). Employers are obligated to minimize worker exposure to these agents as far as possible, and must arrange for medical surveillance of workers exposed to these substances.

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Last updated 25 avril 2024. Database contains 1292 unique substances/entries.
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Substance Name
EC No.
CAS No.
 
Silicon carbide, fibrous
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308076-74-6
 Details
sodium nonadecafluorodecanoate
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3830-45-3
 Details
sodium peroxoborate [containing < 0,1 % (w/w) of particles with an aerodynamic diameter of below 50 μm];sodium peroxoborate [containing ≥ 0,1 % (w/w) of particles with an aerodynamic diameter of below 50 μm]
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-
 Details
sodium peroxoborate [containing ≥ 0,1 % (w/w) of particles with an aerodynamic diameter of below 50 μm]
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-
 Details
sodium peroxoborate hexahydrate [containing < 0,1 % (w/w) of particles with an aerodynamic diameter of below 50 μm];sodium peroxoborate hexahydrate [containing ≥ 0,1 % (w/w) of particles with an aerodynamic diameter of below 50 μm]
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-
 Details
sodium peroxoborate hexahydrate [containing < 0,1 % (w/w) of particles with an aerodynamic diameter of below 50 μm];sodium peroxoborate hexahydrate [containing ≥ 0,1 % (w/w) of particles with an aerodynamic diameter of below 50 μm]
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-
 Details
Strong acid process in the manufacture of isopropyl alcohol
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-
 Details
tributyltin compounds, with the exception of those specified elsewhere in this Annex
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-
 Details
trinickel bis(arsenite)
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74646-29-0
 Details
trinickel tetrasulfide
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12137-12-1
 Details
Work involving dermal exposure to mineral oils that have been used before in internal combustion engines to lubricate and cool the moving parts within the engine
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-
 Details
Work involving exposure to diesel engine exhaust emissions
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-
 Details
Work involving exposure to dusts, fumes and sprays produced during the roasting and electro-refining of cupro-nickel mattes
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-
 Details
Work involving exposure to hardwood dusts
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-
 Details
Work involving exposure to polycyclic aromatic hydrocarbons present in coal soot, coal tar or coal pitch
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-
 Details
Work involving exposure to respirable crystalline silica dust generated by a work process
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-
 Details
zinc chromates including zinc potassium chromate
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C.I. Pigment Yellow 36 EC / List no: 609-398-6 | CAS no: 37300-23-5
Potassium hydroxyoctaoxodizincatedichromate(1-) EC / List no: 234-329-8 | CAS no: 11103-86-9
Zinc dichromate EC / List no: 237-843-0 | CAS no: 14018-95-2
Pentazinc chromate octahydroxide EC / List no: 256-418-0 | CAS no: 49663-84-5
Chromic acid, potassium zinc salt EC / List no: 255-252-6 | CAS no: 41189-36-0
Zinc chromate EC / List no: 236-878-9 | CAS no: 13530-65-9
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-
 Details
(2-ethylhexanoato-O)(isodecanoato-O)nickel
284-351-7
84852-39-1
 Details
(2-ethylhexanoato-O)(isononanoato-O)nickel
287-470-2
85508-45-8
 Details
(3,3'-Dimethyl(1,1'-biphenyl)-4,4'-diyl)diammonium bis(hydrogen sulphate)
265-294-7
64969-36-4
 Details
(isodecanoato-O)(isononanoato-O)nickel
284-348-0
84852-36-8
 Details
(isodecanoato-O)(isooctanoato-O)nickel
285-909-2
85166-19-4
 Details
(isononanoato-O)(isooctanoato-O)nickel
287-471-8
85508-46-9
 Details
(isononanoato-O)(neodecanoato-O)nickel
287-592-6
85551-28-6
 Details
(isooctanoato-O)(neodecanoato-O)nickel
284-347-5
84852-35-7
 Details
(R)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
226-908-9
5543-58-8
 Details
(S)-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2-benzopyrone
226-907-3
5543-57-7
 Details
1,2,3-trichloropropane
202-486-1
96-18-4
 Details
1,2,4-triazole
206-022-9
288-88-0
 Details
1,2-benzenedicarboxylic acid, dihexyl ester, branched and linear
271-093-5
68515-50-4
 Details
1,2-benzenedicarboxylic acid, dipentylester, branched and linear
284-032-2
84777-06-0
 Details
1,2-benzenedicarboxylic acid; di-C6-8-branched alkylesters, C7-rich
276-158-1
71888-89-6
 Details
1,2-benzenedicarboxylic acid; di-C7-11-branched and linear alkylesters
271-084-6
68515-42-4
 Details
1,2-bis(2-methoxyethoxy)ethane; TEGDME; triethylene glycol dimethyl ether; triglyme
203-977-3
112-49-2
 Details
1,2-dibromo-3-chloropropane
202-479-3
96-12-8
 Details
1,2-dibromoethane
203-444-5
106-93-4
 Details
1,2-dichloroethane; ethylene dichloride
203-458-1
107-06-2
 Details
1,2-dichloropropane; propylene dichloride
201-152-2
78-87-5
 Details
1,2-diethoxyethane
211-076-1
629-14-1
 Details
1,2-dihydroxybenzene; pyrocatechol
204-427-5
120-80-9
 Details
1,2-dimethoxyethane; ethylene glycol dimethyl ether; EGDME
203-794-9
110-71-4
 Details
1,3,5-tris(oxiranylmethyl)-1,3,5-triazine-2,4,6(1H,3H,5H)-trione; TGIC
219-514-3
2451-62-9
 Details
1,3-butadiene; buta-1,3-diene
203-450-8
106-99-0
 Details
1,3-dichloro-2-propanol
202-491-9
96-23-1
 Details
1,3-propanesultone; 1,2-oxathiolane 2,2-dioxide
214-317-9
1120-71-4
 Details
1,4,5,8-tetraaminoanthra; quinone; C.I. Disperse Blue 1
219-603-7
2475-45-8
 Details
1,4-Benzenediamine, N,N’-mixed Ph and tolyl derivs.
273-227-8
68953-84-4
 Details
1,4-dichlorobut-2-ene
212-121-8
764-41-0
 Details
1,4-dioxane
204-661-8
123-91-1
 Details
1-bromopropane; n-propyl bromide
203-445-0
106-94-5
 Details
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