carcinogens-mutagens-dir-2004-37

Carc and Muta Directive, Annex I - Substances, Mixtures & Processes

EU. Substances, Mixtures, Related Processes: Annex I & Art. 2, Dir 2004/37/EC (CMRD), as amended by Dir (EU) 2022/431, 16 March 2022

This list contains a non-exhaustive inventory of substances based on Art. 2 carcinogen, mutagen and reprotoxin (CMR) definitions and Annex I of the Carcinogens, Mutagens and Reprotoxins Directive (CMRD). Category 1A and 1B CMRs are derived from the CLP Regulation's Table 3 of Annex VI (1272/2008/EC). Employers are obligated to minimize worker exposure to these agents as far as possible, and must arrange for medical surveillance of workers exposed to these substances.

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Last updated 16 avril 2024. Database contains 1292 unique substances/entries.
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Substance Name
EC No.
CAS No.
 
α-chlorotoluene; benzyl chloride
202-853-6
100-44-7
 Details
α, α, α-trichlorotoluene; benzotrichloride
202-634-5
98-07-7
 Details
α, α, α,4-tetrachlorotoluene; p-chlorobenzotrichloride
226-009-1
5216-25-1
 Details
zinc chromates including zinc potassium chromate
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Pentazinc chromate octahydroxide EC / List no: 256-418-0 | CAS no: 49663-84-5
Chromic acid, potassium zinc salt EC / List no: 255-252-6 | CAS no: 41189-36-0
Zinc dichromate EC / List no: 237-843-0 | CAS no: 14018-95-2
Zinc chromate EC / List no: 236-878-9 | CAS no: 13530-65-9
C.I. Pigment Yellow 36 EC / List no: 609-398-6 | CAS no: 37300-23-5
Potassium hydroxyoctaoxodizincatedichromate(1-) EC / List no: 234-329-8 | CAS no: 11103-86-9
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 Details
Work involving exposure to respirable crystalline silica dust generated by a work process
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 Details
Work involving exposure to polycyclic aromatic hydrocarbons present in coal soot, coal tar or coal pitch
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 Details
Work involving exposure to hardwood dusts
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 Details
Work involving exposure to dusts, fumes and sprays produced during the roasting and electro-refining of cupro-nickel mattes
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 Details
Work involving exposure to diesel engine exhaust emissions
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 Details
Work involving dermal exposure to mineral oils that have been used before in internal combustion engines to lubricate and cool the moving parts within the engine
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 Details
Waste solids, coal-tar pitch coking; Coal Tar Solids Residue [The combination of wastes formed by the coking of bituminous coal tar pitch. It consists predominantly of carbon.]
The combination of wastes formed by the coking of bituminous coal tar pitch. It consists predominantly of carbon.
295-549-8
92062-34-5
 Details
warfarin (ISO); 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one;
201-377-6
81-81-2
 Details
vinyl chloride; chloroethylene
200-831-0
75-01-4
 Details
vinclozolin (ISO); N-3,5-dichlorophenyl-5-methyl-5-vinyl-1,3-oxazolidine-2,4-dione
256-599-6
50471-44-8
 Details
urethane (INN); ethyl carbamate
200-123-1
51-79-6
 Details
trixylyl phosphate
246-677-8
25155-23-1
 Details
trisodium [4'-(8-acetylamino-3,6-disulfonato-2-naphthylazo)-4''-(6-benzoylamino-3-sulfonato2-naphthylazo)-biphenyl 1,3',3'',1'''-tetraolato-O,O',O'',O''']copper(II)
SOLAMINLICHTBLAU VGRL 133
413-590-3
164058-22-4
 Details
tris(2-methoxyethoxy)vinylsilane; 6-(2-methoxyethoxy)-6-vinyl-2,5,7,10-tetraoxa-6-silaundecane
213-934-0
1067-53-4
 Details
tris(2-chloroethyl)phosphate
204-118-5
115-96-8
 Details
trinickel tetrasulfide
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12137-12-1
 Details
trinickel disulfide; nickel subsulfide
234-829-6
12035-72-2
 Details
trinickel boride
234-495-1
12007-02-2
 Details
trinickel bis(orthophosphate)
233-844-5
10381-36-9
 Details
trinickel bis(arsenite)
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74646-29-0
 Details
trinickel bis(arsenate); nickel(II) arsenate
236-771-7
13477-70-8
 Details
trimagnesium;hydroxy(trioxido)silane;hydrate
601-650-3
12001-29-5
 Details
trimagnesium;disodium;dihydroxy(oxo)silane;iron(3+)
601-649-8
12001-28-4
 Details
trilead bis(orthophosphate)
231-205-5
7446-27-7
 Details
trihydrogen hydroxybis[orthosilicato(4-)]trinickelate(3-)
235-688-3
12519-85-6
 Details
triflumizole (ISO); (1E)-N-[4-chloro-2-(trifluoromethyl)phenyl]-1-(1H-imidazol-1-yl)-2-propoxyethanimine
614-708-8
68694-11-1
 Details
triethyl arsenate
TRIETHYLARSENAT; TRIETHYLARSENATE; TRIETHYLARSENATE (TEASAT)
427-700-2
15606-95-8
 Details
tridemorph (ISO); 2,6-dimethyl-4-tridecylmorpholine
246-347-3
24602-86-6
 Details
trichloroethylene; trichloroethene
201-167-4
79-01-6
 Details
tributyltin compounds, with the exception of those specified elsewhere in this Annex
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 Details
triadimenol (ISO); (1RS,2RS;1RS,2SR)-1-(4-chlorophenoxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol; α-tert-butyl-β-(4-chlorophenoxy)-1H-1,2,4-triazole-1-ethanol
259-537-6
55219-65-3
 Details
toluene-2,4-diammonium sulphate; 4-methyl-m-phenylenediamine sulfate
265-697-8
65321-67-7
 Details
thioacetamide
200-541-4
62-55-5
 Details
thiacloprid (ISO); (Z)-3-(6-chloro-3-pyridylmethyl)-1,3-thiazolidin-2-ylidenecyanamide; {(2Z)-3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene}cyanamide
601-147-9
111988-49-9
 Details
theophylline; 1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione
200-385-7
58-55-9
 Details
tetrasodium 3,3'-[[1,1'-biphenyl]-4,4'diylbis(azo)]bis[5-amino-4-hydroxynaphthalene-2,7-disulphonate]; C.I. Direct Blue 6
220-012-1
2602-46-2
 Details
tetrahydrothiopyran-3-carboxaldehyde
THTPA
407-330-8
61571-06-0
 Details
tetrahydro-2-furyl-methanol; tetrahydrofurfuryl alcohol
202-625-6
97-99-4
 Details
tetrafluoroethylene
204-126-9
116-14-3
 Details
tetracarbonylnickel; nickel tetracarbonyl
236-669-2
13463-39-3
 Details
tetraboron disodium heptaoxide, hydrate
235-541-3
12267-73-1
 Details
tellurium dioxide
231-193-1
7446-07-3
 Details
tellurium
236-813-4
13494-80-9
 Details
Tar, coal; Coal tar [The by-product from the destructive distillation of coal. Almost black semisolid. A complex combination of aromatic hydrocarbons, phenolic compounds, nitrogen bases and thiophene.]
The by-product from the destructive distillation of coal. Almost black semisolid. A complex combination of aromatic hydrocarbons, phenolic compounds, nitrogen bases and thiophene.
232-361-7
8007-45-2
 Details
Tar, coal, storage residues; Coal Tar Solids Residue [The deposit removed from crude coal tar storages. Composed primarily of coal tar and carbonaceous particulate matter.]
The deposit removed from crude coal tar storages. Composed primarily of coal tar and carbonaceous particulate matter.
293-764-1
91082-50-7
 Details
Tar, coal, low-temp.; Coal oil [The condensation product obtained by cooling, to approximately ambient temperature, the gas evolved in low temperature (less than 700 °C (1292°F)) destructive distillation of coal. A black viscous liquid denser than water. Composed primarily of condensed ring aromatic hydrocarbons, phenolic compounds, aromatic nitrogen bases, and their alkyl derivatives.]
The condensation product obtained by cooling, to approximately ambient temperature, the gas evolved in low temperature (less than 700°C (1292°F)) destructive distillation of coal. A black viscous liquid denser than water. Composed primarily of condensed ring aromatic hydrocarbons, phenolic compounds, aromatic nitrogen bases, and their alkyl derivatives.
266-025-6
65996-90-9
 Details
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